NASH in lean individuals

R Younes, E Bugianesi - Seminars in liver disease, 2019 - thieme-connect.com
Nonalcoholic fatty liver disease (NAFLD) is generally associated with obesity and the related
comorbidities but it can also develop in subjects with a body mass index (BMI) within the …

Lean NAFLD: an underrecognized outlier

J Wattacheril, AJ Sanyal - Current hepatology reports, 2016 - Springer
Nonalcoholic fatty liver disease (NAFLD) is commonly diagnosed in obese or overweight
individuals. However, lean individuals with NAFLD are not rare but represent one significant …

What are the clinical settings and outcomes of lean NAFLD?

TY Ren, JG Fan - Nature Reviews Gastroenterology & Hepatology, 2021 - nature.com
The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased rapidly and is
associated with obesity in epidemiology and pathogenesis. A new study reports that hepatic …

[HTML][HTML] Nonalcoholic fatty liver disease in lean/nonobese and obese individuals: a comprehensive review on prevalence, pathogenesis, clinical outcomes, and …

AH Patel, D Peddu, S Amin, MI Elsaid… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, with
an estimated prevalence of 25% globally. NAFLD is closely associated with metabolic …

Nonalcoholic fatty liver disease in severely obese subjects

PM Gholam, L Flancbaum, JT Machan… - Official journal of the …, 2007 - journals.lww.com
BACKGROUND Nonalcoholic fatty liver disease (NAFLD) has been consistently associated
with obesity and insulin resistance. Nonalcoholic steatohepatitis (NASH) is a histological …

Caucasian lean subjects with non-alcoholic fatty liver disease share long-term prognosis of non-lean: time for reappraisal of BMI-driven approach?

R Younes, O Govaere, S Petta, L Miele, D Tiniakos… - Gut, 2022 - gut.bmj.com
Objective The full phenotypic expression of non-alcoholic fatty liver disease (NAFLD) in lean
subjects is incompletely characterised. We aimed to investigate prevalence, characteristics …

Lean non-alcoholic fatty liver disease (lean NAFLD): characteristics, metabolic outcomes and risk factors from a 7-year prospective, community cohort study from Sri …

MA Niriella, A Kasturiratne, A Pathmeswaran… - Hepatology …, 2019 - Springer
Introduction While patients with non-alcoholic fatty liver disease (NAFLD) are mostly
overweight or obese, some are lean. Methods In a community-based follow-up study …

Diagnosis and classification of non‐alcoholic fatty liver disease and non‐alcoholic steatohepatitis: Current concepts and remaining challenges

E Hashimoto, K Tokushige, J Ludwig - Hepatology research, 2015 - Wiley Online Library
The high prevalence of non‐alcoholic fatty liver disease (NAFLD) has made the condition an
important public health issue. Two clinical entities are manifestations of NAFLD, namely, non …

Lean patients with non-alcoholic fatty liver disease have a severe histological phenotype similar to obese patients

L Denkmayr, A Feldman, L Stechemesser… - Journal of clinical …, 2018 - mdpi.com
A small proportion of lean patients develop non-alcoholic fatty liver disease (NAFLD). We
aimed to report the histological picture of lean NAFLD in comparison to overweight and …

Non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH): diagnosis and clinical course

H Cortez-Pinto, ME Camilo - Best practice & research Clinical …, 2004 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a frequent syndrome encompassing fatty liver
alone and steatohepatitis (NASH). Often asymptomatic, the suspicion arises because of …