Nanocarrier fabrication and macromolecule drug delivery: challenges and opportunities

V Agrahari, V Agrahari, AK Mitra - Therapeutic delivery, 2016 - Taylor & Francis
Macromolecules (proteins/peptides) have the potential for the development of new
therapeutics. Due to their specific mechanism of action, macromolecules can be …

Nanoscale carriers for targeted delivery of drugs and therapeutic biomolecules

C Kiparissides, O Kammona - The Canadian Journal of …, 2013 - Wiley Online Library
This review highlights the recent developments in the area of nanocarrier‐based targeted
delivery systems for both conventional drugs and therapeutic agents of increased …

Targeted delivery of protein drugs by nanocarriers

R Solaro, F Chiellini, A Battisti - Materials, 2010 - mdpi.com
Recent advances in biotechnology demonstrate that peptides and proteins are the basis of a
new generation of drugs. However, the transportation of protein drugs in the body is limited …

Recent advances in nanocarrier-based mucosal delivery of biomolecules

O Kammona, C Kiparissides - Journal of controlled release, 2012 - Elsevier
This review highlights the recent developments in the area of nanocarrier-based mucosal
delivery of therapeutic biomolecules and antigens. Macromolecular drugs have the unique …

Rational design of nanocarriers for intracellular protein delivery

X Qin, C Yu, J Wei, L Li, C Zhang, Q Wu… - Advanced …, 2019 - Wiley Online Library
Protein/antibody therapeutics have exhibited the advantages of high specificity and activity
even at an extremely low concentration compared to small molecule drugs. However, they …

Role of nanotechnology in delivery of protein and peptide drugs

S Patil, I Vhora, J Amrutiya, R Lalani… - Current pharmaceutical …, 2015 - ingentaconnect.com
The advent of recombinant DNA technology and computational designing has fueled the
emergence of proteins and peptides as a new class of modern therapeutics such as …

Nanocarrier-based delivery of peptides: challenges and way forward

VP Chavda, PC Balar, P Dodiya, J Bojarska - Nanomedicine, 2023 - Taylor & Francis
In recent years, peptides have emerged as a distinct class of therapeutic agents due to their
unique intrinsic advantages, as well as scientific and technological progress that has helped …

New aspects of nanopharmaceutical delivery systems

PD Marcato, N Durán - Journal of nanoscience and …, 2008 - ingentaconnect.com
Nanobiotechnology, involving biological systems manufactured at the molecular level, is a
multidisciplinary field that has fostered the development of nanoscaled pharmaceutical …

Particle carriers for controlled release of peptides

EY Jiang, ST Desroches, AG Mikos - Journal of Controlled Release, 2023 - Elsevier
There has been growing discovery and use of therapeutic peptides in drug delivery and
tissue engineering. Peptides are smaller than proteins and can be formulated into drug …

Potential and applications of nanocarriers for efficient delivery of biopharmaceuticals

A Zeb, I Rana, HI Choi, CH Lee, SW Baek, CW Lim… - Pharmaceutics, 2020 - mdpi.com
During the past two decades, the clinical use of biopharmaceutical products has markedly
increased because of their obvious advantages over conventional small-molecule drug …