[HTML][HTML] A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation
The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in
perception, cognition, emotion, and learning. We profiled∼ 1.3 million cells covering the …
perception, cognition, emotion, and learning. We profiled∼ 1.3 million cells covering the …
Genomic anatomy of the hippocampus
CL Thompson, SD Pathak, A Jeromin, LL Ng… - Neuron, 2008 - cell.com
Availability of genome-scale in situ hybridization data allows systematic analysis of genetic
neuroanatomical architecture. Within the hippocampus, electrophysiology and lesion and …
neuroanatomical architecture. Within the hippocampus, electrophysiology and lesion and …
Resolving cellular and molecular diversity along the hippocampal anterior-to-posterior axis in humans
The hippocampus supports many facets of cognition, including learning, memory, and
emotional processing. Anatomically, the hippocampus runs along a longitudinal axis …
emotional processing. Anatomically, the hippocampus runs along a longitudinal axis …
Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
The hippocampal-entorhinal system supports cognitive functions, has lifelong neurogenic
capabilities in many species, and is selectively vulnerable to Alzheimer's disease. To …
capabilities in many species, and is selectively vulnerable to Alzheimer's disease. To …
A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan
The molecular diversity of glia in the human hippocampus and their temporal dynamics over
the lifespan remain largely unknown. Here, we performed single-nucleus RNA sequencing …
the lifespan remain largely unknown. Here, we performed single-nucleus RNA sequencing …
Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization
The hippocampus consists of a series of cytoarchitecturally discrete subregions that can be
distinguished from one another on the basis of morphology, connectivity, and …
distinguished from one another on the basis of morphology, connectivity, and …
Human-specific transcriptional networks in the brain
G Konopka, T Friedrich, J Davis-Turak, K Winden… - Neuron, 2012 - cell.com
Understanding human-specific patterns of brain gene expression and regulation can
provide key insights into human brain evolution and speciation. Here, we use next …
provide key insights into human brain evolution and speciation. Here, we use next …
A single-cell RNA sequencing study reveals cellular and molecular dynamics of the hippocampal neurogenic niche
Adult neurogenesis in the murine dentate gyrus occurs in a specialized microenvironment
that sustains the generation of neurons during life. To fully understand adult neurogenesis, it …
that sustains the generation of neurons during life. To fully understand adult neurogenesis, it …
Heterogeneity within classical cell types is the rule: lessons from hippocampal pyramidal neurons
MS Cembrowski, N Spruston - Nature Reviews Neuroscience, 2019 - nature.com
The mechanistic operation of brain regions is often interpreted by partitioning constituent
neurons into 'cell types'. Historically, such cell types were broadly defined by their …
neurons into 'cell types'. Historically, such cell types were broadly defined by their …
Transcriptomic perspectives on neocortical structure, development, evolution, and disease
The cerebral cortex is the source of our most complex cognitive capabilities and a
vulnerable target of many neurological and neuropsychiatric disorders. Transcriptomics …
vulnerable target of many neurological and neuropsychiatric disorders. Transcriptomics …