Gender differences in efficacy and safety of antiplatelet strategies for acute coronary syndromes

G Occhipinti, A Greco, DJ Angiolillo… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Dual antiplatelet therapy (DAPT) represents the cornerstone of secondary
prevention in patients presenting with acute coronary syndrome (ACS) and undergoing …

Role of gender in dual antiplatelet therapy after acute coronary syndrome

J Mallidi, K Lata - Current atherosclerosis reports, 2019 - Springer
Abstract Purpose of Review The effect of gender on use of dual antiplatelet therapy (DAPT)
in treatment of acute coronary syndrome (ACS) is not well established. The purpose of this …

Escalation and de-escalation of antiplatelet therapy after acute coronary syndrome or PCI: Available evidence and implications for practice

F Gragnano, A Capolongo, F Terracciano… - Journal of Clinical …, 2022 - mdpi.com
Dual antiplatelet therapy (DAPT) is the gold standard for the antithrombotic management of
patients with an acute coronary syndrome (ACS) or undergoing percutaneous coronary …

A review of sex-specific benefits and risks of antithrombotic therapy in acute coronary syndrome

WT Wang, SK James, TY Wang - European heart journal, 2017 - academic.oup.com
Over the past decade, more men than women have shown improved outcomes from
antithrombotic therapies after acute coronary syndrome (ACS), which raises the question of …

Understanding Differences in Sex-Based Outcomes with Dual Antiplatelet Therapy After Percutaneous Coronary Intervention

I Akin, N Hamdani, I El-Battrawy - Drugs, 2024 - Springer
Cardiovascular diseases are the leading causes of mortality, and several medical and non-
medical pillars play a pivotal role in improving prognosis. Inhibition of platelet reactivity in …

Women and the management of acute coronary syndrome

P Ostadal, B Ostadal - Canadian journal of physiology and …, 2012 - cdnsciencepub.com
Coronary heart disease (CHD) is the leading cause of morbidity and mortality in both men
and women in the developed countries. Despite this fact, females are still under-represented …

Sex-Based Outcomes of Dual-Antiplatelet Therapy After Percutaneous Coronary Intervention: A Pairwise and Network Meta-Analysis

TA Agbaedeng, JJ Noubiap, KA Roberts, DP Chew… - Drugs, 2024 - Springer
Background Although dual antiplatelet therapy (DAPT) improves the outcomes of patients
undergoing percutaneous coronary intervention (PCI), sex-specific differences in efficacy …

Gender and outcomes following guided de-escalation of antiplatelet treatment in acute coronary syndrome patients: the TROPICAL-ACS gender substudy

L Gross, D Kupka, D Trenk, T Geisler… - Thrombosis and …, 2019 - thieme-connect.com
Objectives This prespecified analysis of the TROPICAL-ACS trial aimed to assess the impact
of gender on clinical outcomes and platelet reactivity (PR) following guided de-escalation of …

Abbreviated or standard dual antiplatelet therapy by sex in patients at high bleeding risk: a prespecified secondary analysis of a randomized clinical trial

A Landi, M Alasnag, D Heg, E Frigoli, FTN Malik… - JAMA …, 2024 - jamanetwork.com
Importance Abbreviated dual antiplatelet therapy (DAPT) reduces bleeding with no increase
in ischemic events in patients at high bleeding risk (HBR) undergoing percutaneous …

De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an …

DA Gorog, JL Ferreiro, I Ahrens, J Ako… - Nature Reviews …, 2023 - nature.com
Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes
undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y …