Genome-wide identification and predictive modeling of polyadenylation sites in eukaryotes
Abstract Polyadenylation [poly (A)] is a vital step in post-transcriptional processing of pre-
mRNA. Alternative polyadenylation is a widespread mechanism of regulating gene …
mRNA. Alternative polyadenylation is a widespread mechanism of regulating gene …
Prediction of mRNA polyadenylation sites by support vector machine
Abstract mRNA polyadenylation is responsible for the 3′ end formation of most mRNAs in
eukaryotic cells and is linked to termination of transcription. Prediction of mRNA …
eukaryotic cells and is linked to termination of transcription. Prediction of mRNA …
A survey on methods for predicting polyadenylation sites from DNA sequences, bulk RNA-seq, and single-cell RNA-seq
Alternative polyadenylation (APA) plays important roles in modulating mRNA stability,
translation, and subcellular localization, and contributes extensively to shaping eukaryotic …
translation, and subcellular localization, and contributes extensively to shaping eukaryotic …
PolyASite 2.0: a consolidated atlas of polyadenylation sites from 3′ end sequencing
CJ Herrmann, R Schmidt, A Kanitz, P Artimo… - Nucleic acids …, 2020 - academic.oup.com
Generated by 3′ end cleavage and polyadenylation at alternative polyadenylation (poly
(A)) sites, alternative terminal exons account for much of the variation between human …
(A)) sites, alternative terminal exons account for much of the variation between human …
[HTML][HTML] Aptardi predicts polyadenylation sites in sample-specific transcriptomes using high-throughput RNA sequencing and DNA sequence
R Lusk, E Stene, F Banaei-Kashani, B Tabakoff… - Nature …, 2021 - nature.com
Annotation of polyadenylation sites from short-read RNA sequencing alone is a challenging
computational task. Other algorithms rooted in DNA sequence predict potential …
computational task. Other algorithms rooted in DNA sequence predict potential …
DeepPASTA: deep neural network based polyadenylation site analysis
Motivation Alternative polyadenylation (polyA) sites near the 3′ end of a pre-mRNA create
multiple mRNA transcripts with different 3′ untranslated regions (3′ UTRs). The sequence …
multiple mRNA transcripts with different 3′ untranslated regions (3′ UTRs). The sequence …
A survey on identification and quantification of alternative polyadenylation sites from RNA-seq data
Alternative polyadenylation (APA) has been implicated to play an important role in post-
transcriptional regulation by regulating mRNA abundance, stability, localization and …
transcriptional regulation by regulating mRNA abundance, stability, localization and …
QuantifyPoly (A): reshaping alternative polyadenylation landscapes of eukaryotes with weighted density peak clustering
The dynamic choice of different polyadenylation sites in a gene is referred to as alternative
polyadenylation, which functions in many important biological processes. Large-scale …
polyadenylation, which functions in many important biological processes. Large-scale …
A classification-based prediction model of messenger RNA polyadenylation sites
Messenger RNA polyadenylation is one of the essential processing steps during eukaryotic
gene expression. The site of polyadenylation [(poly (A) site] marks the end of a transcript …
gene expression. The site of polyadenylation [(poly (A) site] marks the end of a transcript …
[HTML][HTML] Sequence determinants in human polyadenylation site selection
M Legendre, D Gautheret - BMC genomics, 2003 - Springer
Background Differential polyadenylation is a widespread mechanism in higher eukaryotes
producing mRNAs with different 3'ends in different contexts. This involves several alternative …
producing mRNAs with different 3'ends in different contexts. This involves several alternative …