Shared genetic links between frontotemporal dementia and psychiatric disorders
C Li, D Pang, J Lin, T Yang, H Shang - BMC medicine, 2022 - Springer
Background Epidemiological and clinical studies have suggested comorbidity between
frontotemporal dementia (FTD) and psychiatric disorders. FTD patients carrying specific …
frontotemporal dementia (FTD) and psychiatric disorders. FTD patients carrying specific …
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases
Background Clinical, pathological and genetic overlap between sporadic frontotemporal
dementia (FTD), Alzheimer's disease (AD) and Parkinson's disease (PD) has been …
dementia (FTD), Alzheimer's disease (AD) and Parkinson's disease (PD) has been …
[HTML][HTML] Gene expression imputation across multiple tissue types provides insight into the genetic architecture of frontotemporal dementia and its clinical subtypes
Background The etiology of frontotemporal dementia (FTD) is poorly understood. To identify
genes with predicted expression levels associated with FTD, we integrated summary …
genes with predicted expression levels associated with FTD, we integrated summary …
The relationship between schizophrenia and frontotemporal dementia
JJ Cooper, F Ovsiew - Journal of Geriatric Psychiatry and …, 2013 - journals.sagepub.com
Schizophrenia is a relatively common disorder diagnosed by the presentation of psychotic
symptoms in the absence of identifiable neurologic or other organic cause. Frontotemporal …
symptoms in the absence of identifiable neurologic or other organic cause. Frontotemporal …
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
Background Converging evidence suggests that immune-mediated dysfunction plays an
important role in the pathogenesis of frontotemporal dementia (FTD). Although genetic …
important role in the pathogenesis of frontotemporal dementia (FTD). Although genetic …
Frontotemporal dementia and its subtypes: a genome-wide association study
Background Frontotemporal dementia (FTD) is a complex disorder characterised by a broad
range of clinical manifestations, differential pathological signatures, and genetic variability …
range of clinical manifestations, differential pathological signatures, and genetic variability …
Distinct neuroanatomical correlates of neuropsychiatric symptoms in the three main forms of genetic frontotemporal dementia in the GENFI cohort
L Sellami, M Bocchetta, M Masellis… - Journal of …, 2018 - content.iospress.com
Background: The overlap between frontotemporal dementia (FTD) and primary psychiatric
disorders has been brought to light by reports of prominent neuropsychiatric symptoms …
disorders has been brought to light by reports of prominent neuropsychiatric symptoms …
Genome-wide association study of frontotemporal dementia identifies a C9ORF72 haplotype with a median of 12-G4C2 repeats that predisposes to pathological …
Genetic factors play a major role in frontotemporal dementia (FTD). The majority of FTD
cannot be genetically explained yet and it is likely that there are still FTD risk loci to be …
cannot be genetically explained yet and it is likely that there are still FTD risk loci to be …
Clinico-genetic findings in 509 frontotemporal dementia patients
M Wagner, G Lorenz, AE Volk, T Brunet… - Molecular …, 2021 - nature.com
Frontotemporal dementia (FTD) is a clinically and genetically heterogeneous disorder. To
which extent genetic aberrations dictate clinical presentation remains elusive. We …
which extent genetic aberrations dictate clinical presentation remains elusive. We …
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA …
E Taskesen, A Mishra, S van der Sluis, R Ferrari… - Scientific reports, 2017 - nature.com
Frontotemporal dementia (FTD) is a neurodegenerative disorder predominantly affecting the
frontal and temporal lobes. Genome-wide association studies (GWAS) on FTD identified …
frontal and temporal lobes. Genome-wide association studies (GWAS) on FTD identified …
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