Systems biology: a therapeutic target for tumor therapy

A Reichle, T Vogt - From Molecular to Modular Tumor Therapy: Tumors are …, 2010 - Springer
Tumor-related activities that seem to be operationally induced by the division of function,
such as inflammation, neoangiogenesis, Warburg effect, immune response, extracellular …

[HTML][HTML] Systems biology: a therapeutic target for tumor therapy

A Reichle, T Vogt - Cancer Microenvironment, 2008 - Springer
Tumor-related activities that seem to be operationally induced by the division of function,
such as inflammation, neoangiogenesis, Warburg effect, immune response, extracellular …

Tumor Systems Need to be Rendered Usable for a New Action-Theoretical Abstraction: The Starting Point for Novel Therapeutic Options

A Reichle - From Molecular to Modular Tumor Therapy: Tumors are …, 2010 - Springer
A tumor system not only consists of diverse cell types but also comprises all components of
action insofar that these components are oriented in terms of diverse cell types. Thus, it is …

Uncovering tumor systems biology by biomodulatory therapy strategies

A Reichle - From Molecular to Modular Tumor Therapy: Tumors are …, 2010 - Springer
How can get structured therapies in metastatic cancer a source for detecting tumor-
associated systems-biological processes as adjustable sizes available for biomodulatory …

Future of personalized medicine in oncology: a systems biology approach

AM Gonzalez-Angulo, BTJ Hennessy… - Journal of clinical …, 2010 - ascopubs.org
The development of cost-effective technologies able to comprehensively assess DNA, RNA,
protein, and metabolites in patient tumors has fueled efforts to tailor medical care. Indeed …

The challenge of translating system biology into targeted therapy of cancer

AJ Conforte, M Magalhães, TM Tilli… - Theoretical and Applied …, 2018 - Springer
Translational medicine has been leveraging new technologies and tools for data analysis to
promote the development of new treatments. Integration of translational medicine with …

From molecular to modular, from theme-dependent to evolution-adjusted tumor therapy

A Reichle, GC Hildebrandt - From Molecular to Modular Tumor Therapy …, 2010 - Springer
The successful implementation of biomodulatory therapies for controlling a wide variety of
metastatic types of cancer has been demonstrated in multiple clinical phase II trials. These …

Cancer systems biology: embracing complexity to develop better anticancer therapeutic strategies

W Du, O Elemento - Oncogene, 2015 - nature.com
The transformation of normal cells into cancer cells and maintenance of the malignant state
and phenotypes are associated with genetic and epigenetic deregulations, altered cellular …

A methodological approach to personalized therapies in metastatic cancer

A Reichle, T Vogt, GC Hildebrandt - From Molecular to Modular Tumor …, 2010 - Springer
Personalized medicine should consist of a methodological therapy approach. Therefore,
metastatic tumors have to be rendered usable for innovative action-theoretical therapy …

Cancer systems biology: a peek into the future of patient care?

HMJ Werner, GB Mills, PT Ram - Nature reviews Clinical oncology, 2014 - nature.com
Traditionally, scientific research has focused on studying individual events, such as single
mutations, gene function, or the effect that mutating one protein has on a biological …