Abstract Tatton-Brown–Rahman syndrome (TBRS) is a rare congenital genetic disorder
caused by autosomal dominant pathogenic variants in the DNA methyltransferase DNMT3A …

Abstract Tatton‐Brown‐Rahman syndrome is an autosomal dominant overgrowth syndrome
caused by pathogenic DNMT3A variants in the germline. Clinical findings of tall stature due …

Background Tatton-Brown-Rahman syndrome (TBRS) is a rare disorder, caused by
DNMT3A heterozygous pathogenic variants, and first described in 2014. TBRS is …

Tatton-Brown-Rahman syndrome (TBRS; OMIM# 615879) is a rare overgrowth and
intellectual disability (ID) syndrome caused by heterozygous loss-of-function variants in the …

Pathogenic variants in DNMT3A are most commonly associated with Tatton-Brown-Rahman
Syndrome (TBRS), but includes other phenotypes such as Heyn-Sproul-Jackson syndrome …

Tatton‐Brown–Rahman syndrome (TBRS) was recently described in 13 isolated cases with
de novo mutations in the DNMT3A gene. This autosomal dominant condition is …

Abstract Tatton–Brown–Rahman syndrome (TBRS) is a rare autosomal dominant
overgrowth syndrome first reported in 2014 and caused by pathogenic variants in the DNA …

Tatton–Brown–Rahman syndrome is a rare autosomal dominant hereditary disease caused
by pathogenic variants in the DNMT3A gene, which is an important participant in epigenetic …

Background Recently a novel syndromic form of overgrowth with intellectual disability and
distinct facial features was identified caused by constitutional mutations in the epigenetic …

Background Tatton-Brown-Rahman syndrome (TBRS; OMIM 615879), also known as DNA
methyltransferase 3 alpha (DNMT3A)-overgrowth syndrome (DOS), was first described by …