Identifying factors contributing to increased susceptibility to COVID-19 risk: a systematic review of Mendelian randomization studies

S Luo, Y Liang, THT Wong… - International journal …, 2022 - academic.oup.com
Background To summarize modifiable factors for coronavirus disease 2019 (COVID-19)
suggested by Mendelian randomization studies. Methods In this systematic review, we …

[HTML][HTML] Modifiable lifestyle factors and severe COVID-19 risk: a Mendelian randomisation study

S Li, X Hua - BMC medical genomics, 2021 - Springer
Background Lifestyle factors including obesity and smoking are suggested to be correlated
with increased risk of COVID-19 severe illness or related death. However, whether these …

[HTML][HTML] Extensive Mendelian randomization study identifies potential causal risk factors for severe COVID-19

Y Sun, J Zhou, K Ye - Communications Medicine, 2021 - nature.com
Background Identifying causal risk factors for severe coronavirus disease 2019 (COVID-19)
is critical for its prevention and treatment. Many associated pre-existing conditions and …

A phenome‐wide investigation of risk factors for severe COVID‐19

A Baranova, H Cao, S Teng… - Journal of Medical …, 2023 - Wiley Online Library
With the continued spread of COVID‐19 globally, it is crucial to identify the potential risk or
protective factors associated with COVID‐19. Here, we performed genetic correlation …

Association of smoking, lung function and COPD in COVID‐19 risk: a two‐step Mendelian randomization study

SL Au Yeung, AM Li, B He, KO Kwok, CM Schooling - Addiction, 2022 - Wiley Online Library
Abstract Background and Aims Smoking increases the risk of severe COVID‐19, but whether
lung function or chronic obstructive pulmonary disease (COPD) mediate the underlying …

[HTML][HTML] Cardiometabolic risk factors for COVID-19 susceptibility and severity: a Mendelian randomization analysis

A Leong, JB Cole, LN Brenner, JB Meigs… - PLoS …, 2021 - journals.plos.org
Background Epidemiological studies report associations of diverse cardiometabolic
conditions including obesity with COVID-19 illness, but causality has not been established …

Proteomic profiling identifies novel proteins for genetic risk of severe COVID-19: the Atherosclerosis Risk in Communities Study

BT Steffen, JS Pankow, PL Lutsey… - Human molecular …, 2022 - academic.oup.com
Background Genome-wide association studies have identified six genetic variants
associated with severe COVID-19, yet the mechanisms through which they may affect …

Genetic risk factors and COVID-19 severity in Brazil: results from BRACOVID study

AC Pereira, TM Bes, M Velho, E Marques… - Human molecular …, 2022 - academic.oup.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has changed the paradigms
for disease surveillance and rapid deployment of scientific-based evidence for …

[HTML][HTML] Human genetic factors associated with susceptibility to SARS-CoV-2 infection and COVID-19 disease severity

C Anastassopoulou, Z Gkizarioti, GP Patrinos… - Human genomics, 2020 - Springer
Background The emergence of the novel coronavirus in Wuhan, Hubei Province, China, in
December 2019 marked the synchronization of the world to a peculiar clock that is counting …

Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity

K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …