Introduction: Oocytes and follicular somatic cells within the ovarian follicle are altered during
maturation and after exposure to culture in vitro. In the present study, we used a nontargeted …

Introduction: Oocyte quality and fertility decline with advanced maternal age. During
maturation within the ovarian follicle, the oocyte relies on the associated somatic cells …

Background Maturation of oocytes under in vitro conditions (IVM) results in impaired
developmental competence compared to oocytes matured in vivo. As oocytes are closely …

Advanced maternal age is associated with a decline in fertility and oocyte quality. We used
novel metabolic microsensors to assess effects of mare age on single oocyte and embryo …

A crucial component of Assisted Reproductive Technologies (ART) is the assessment of
oocyte developmental potential, to allow selection of those oocytes most likely to result in …

Simple Summary Commercial in vitro embryo production in horses by ICSI (intracytoplasmic
sperm injection) is currently used to produce embryos clinically. However, the successful …

Metabolic coupling between oocytes and the surrounding somatic cells allows for normal
two-way communication, and their interactions is necessary for generating developmentally …

The aim of this study was to characterize the composition of follicular fluid (FF) collected from
the small and large follicles of three mammalian species, Bos taurus, Sus scrofa domesticus …

Well-balanced and orderly metabolism is a crucial prerequisite for promoting oogenesis.
Involvement of single metabolites in oocyte development has been widely reported; …

During folliculogenesis, follicular fluid (FF) supplies many of the nutrients, metabolic
compounds, and signaling molecules that are essential for the accumulation of metabolic …