Overexpression of TRPM7 promotes the therapeutic effect of curcumin in wound healing through the STAT3/SMAD3 signaling pathway in human fibroblasts
H Zhang, H Li, H Wang, S Lei, L Yan - Burns, 2023 - Elsevier
Objective Curcumin, a natural extract from the rhizomes of Curcuma longa, is also known as
a curcuminoid. Curcumin has been studied as a therapeutic drug for wound healing …
a curcuminoid. Curcumin has been studied as a therapeutic drug for wound healing …
Upregulation of TRPM8 can promote the colon cancer liver metastasis through mediating Akt/GSK‐3 signal pathway
JJ Liu, LZ Li, P Xu - Biotechnology and Applied Biochemistry, 2022 - Wiley Online Library
This study aims to clarify the function of transient receptor potential melastatin 8 (TRPM8) in
colon cancer liver metastasis. First, TRPM8 expression was determined by Western blotting …
colon cancer liver metastasis. First, TRPM8 expression was determined by Western blotting …
[HTML][HTML] Tm7sf2 may participate in the healing of burn wounds
N Lei, P Wang, Q Meng - Molecular Medicine Reports, 2016 - spandidos-publications.com
The transmembrane 7 superfamily member 2 (Tm7sf2) gene been reported to be involved in
the reduced cholesterol levels of patients with large burn areas. To investigate the …
the reduced cholesterol levels of patients with large burn areas. To investigate the …
TRPM8 promotes aggressiveness of breast cancer cells by regulating EMT via activating AKT/GSK-3β pathway
J Liu, Y Chen, S Shuai, D Ding, R Li, R Luo - Tumor Biology, 2014 - Springer
Breast cancer already taken the first place of incidence in Chinese female cancer patients.
TRPM8 is found to be over-expressed in breast cancer, but whether it promotes breast …
TRPM8 is found to be over-expressed in breast cancer, but whether it promotes breast …
Roles of TRPM4 in immune responses in keratinocytes and identification of a novel TRPM4-activating agent
KO Saito, F Fujita, M Toriyama, RA Utami, Z Guo… - Biochemical and …, 2023 - Elsevier
The skin is a protective interface between the internal organs and environment and functions
not only as a physical barrier but also as an immune organ. However, the immune system in …
not only as a physical barrier but also as an immune organ. However, the immune system in …
Suppression of cortical TRPM7 protein attenuates oxidative damage after traumatic brain injury via Akt/endothelial nitric oxide synthase pathway
HL Xu, MD Liu, XH Yuan, CX Liu - Neurochemistry International, 2018 - Elsevier
Neuronal death after traumatic brain injury (TBI) is a complex process resulting from a
combination of factors, many of which are still unknown. Transient receptor potential …
combination of factors, many of which are still unknown. Transient receptor potential …
Stimulating TRPM7 suppresses cancer cell proliferation and metastasis by inhibiting autophagy
Y Xing, X Wei, MM Wang, Y Liu, Z Sui, X Wang… - Cancer letters, 2022 - Elsevier
The transient receptor potential melastatin-subfamily member 7 (TRPM7) is a ubiquitous
cation channel possessing kinase activity. TRPM7 mediates a variety of physiological …
cation channel possessing kinase activity. TRPM7 mediates a variety of physiological …
Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of …
Abstract Transient Receptor Potential (TRP) channels are mostly Ca2+ permeable cation
channels. Transient Receptor Potential Melastatin-like 2 (TRPM2) is expressed in …
channels. Transient Receptor Potential Melastatin-like 2 (TRPM2) is expressed in …
[HTML][HTML] TRPM7 promotes the epithelial–mesenchymal transition in ovarian cancer through the calcium-related PI3K/AKT oncogenic signaling
L Liu, N Wu, Y Wang, X Zhang, B Xia, J Tang… - Journal of Experimental …, 2019 - Springer
Background The epithelial-mesenchymal transition (EMT) is crucial for metastasis and
positively regulated by calcium-related signaling. The melastatin-related transient receptor …
positively regulated by calcium-related signaling. The melastatin-related transient receptor …
[HTML][HTML] TRPM8 in the negative regulation of TNFα expression during cold stress
XP Wang, X Yu, XJ Yan, F Lei, YS Chai, JF Jiang… - Scientific reports, 2017 - nature.com
Abstract Transient Receptor Potential Melastatin-8 (TRPM8) reportedly plays a fundamental
role in a variety of processes including cold sensation, thermoregulation, pain transduction …
role in a variety of processes including cold sensation, thermoregulation, pain transduction …
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