Combating implant infections: shifting focus from bacteria to host

S Amin Yavari, SM Castenmiller… - Advanced …, 2020 - Wiley Online Library
The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …

Immunomodulatory biomaterials for implant-associated infections: from conventional to advanced therapeutic strategies

J Dong, W Wang, W Zhou, S Zhang, M Li, N Li… - Biomaterials …, 2022 - spj.science.org
Implant-associated infection (IAI) is increasingly emerging as a serious threat with the
massive application of biomaterials. Bacteria attached to the surface of implants are often …

Biomaterial-associated infection: locating the finish line in the race for the surface

HJ Busscher, HC van der Mei, G Subbiahdoss… - Science translational …, 2012 - science.org
Biomaterial-associated infections occur on both permanent implants and temporary devices
for restoration or support of human functions. Despite increasing use of biomaterials in an …

[HTML][HTML] Adaptive antibacterial biomaterial surfaces and their applications

W Ahmed, Z Zhai, C Gao - Materials Today Bio, 2019 - Elsevier
Bacterial infections on the implant surface may eventually lead to biofilm formation​ and
thus threaten the use of implants in body. Despite efficient host immune system, the implant …

Anti-periprosthetic infection strategies: from implant surface topographical engineering to smart drug-releasing coatings

A Ghimire, J Song - ACS applied materials & interfaces, 2021 - ACS Publications
Despite advanced implant sterilization and aseptic surgical techniques, periprosthetic
bacterial infection remains a major challenge for orthopedic and dental implants. Bacterial …

Implantable antimicrobial biomaterials for local drug delivery in bone infection models

JD Caplin, AJ García - Acta biomaterialia, 2019 - Elsevier
Increased use of implantable biomedical devices demonstrates their potential in treating a
wide variety of ailments and disorders in bone trauma and orthopaedic, reconstructive, and …

Reducing implant-related infections: active release strategies

EM Hetrick, MH Schoenfisch - Chemical Society Reviews, 2006 - pubs.rsc.org
Despite sterilization and aseptic procedures, bacterial infection remains a major impediment
to the utility of medical implants including catheters, artificial prosthetics, and subcutaneous …

A review of the biomaterials technologies for infection-resistant surfaces

D Campoccia, L Montanaro, CR Arciola - Biomaterials, 2013 - Elsevier
Anti-infective biomaterials need to be tailored according to the specific clinical application.
All their properties have to be tuned to achieve the best anti-infective performance together …

Tuning surface topographies on biomaterials to control bacterial infection

S Khalid, A Gao, G Wang, PK Chu, H Wang - Biomaterials Science, 2020 - pubs.rsc.org
Microbial contamination and subsequent formation of biofilms frequently cause failure of
surgical implants and a good understanding of the bacteria–surface interactions is vital to …

Multifunctional coatings and nanotopographies: toward cell instructive and antibacterial implants

C Mas‐Moruno, B Su, MJ Dalby - Advanced healthcare …, 2019 - Wiley Online Library
In biomaterials science, it is nowadays well accepted that improving the biointegration of
dental and orthopedic implants with surrounding tissues is a major goal. However, implant …