Cytotoxic T cells are of central importance in the immune system's response to disease.
They recognize defective cells by binding to peptides presented on the cell surface by MHC …

Computational prediction of the peptides presented on major histocompatibility complex
(MHC) class I proteins is an important tool for studying T cell immunity. The data available to …

The identification of MHC class II restricted peptide epitopes is an important goal in
immunological research. A number of computational tools have been developed for this …

Background Binding of peptides to MHC class I molecules (MHC-I) is essential for antigen
presentation to cytotoxic T-cells. Results Here, we demonstrate how a simple alignment step …

Major histocompatibility complex (MHC) molecules are expressed on the cell surface, where
they present peptides to T cells, which gives them a key role in the development of T-cell …

A number of machine learning-based predictors have been developed for identifying
immunogenic T-cell epitopes based on major histocompatibility complex (MHC) class I and II …

Major histocompatibility complex class II (MHC‐II) molecules are expressed on the surface
of professional antigen‐presenting cells where they display peptides to T helper cells, which …

Major histocompatibility complex II (MHC II) molecules play a vital role in the onset and
control of cellular immunity. In a highly selective process, MHC II presents peptides derived …

A key event in the generation of a cellular response against malicious organisms through
the endocytic pathway is binding of peptidic antigens by major histocompatibility complex …

Predicting the binding affinity of major histocompatibility complex I (MHC I) proteins and their
peptide ligands is important for vaccine design. We introduce an open-source package for …