Amyotrophic lateral sclerosis (ALS) is a chronic, progressive neurodegenerative disease
characterized by the loss of motor neurons. Dysregulated peripheral immunity has been …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects
upper motor neurons (MNs) comprising the corticospinal tract and lower MNs arising from …

The prevailing motor neuron-centric view of amyotrophic lateral sclerosis (ALS)
pathogenesis could be an important factor in the failure to identify disease-modifying therapy …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that leads
to neuronal death in the brain and spinal cord. Over the last decades, evidence has …

Neurodegenerative disorders are characterized by the selective vulnerability and
progressive loss of discrete neuronal populations. Non-neuronal cells appear to significantly …

Amyotrophic lateral sclerosis (ALS), a devastating motor neuron disease involving complex
genetic and environmental factors, is associated with neuroinflammation. Preclinical and …

Amyotrophic lateral sclerosis (ALS) is a debilitating and rapidly fatal neurodegenerative
disease. Despite decades of research and many new insights into disease biology over the …

Neurological dysfunction and motor neuron degeneration in amyotrophic lateral sclerosis
(ALS) is strongly associated with neuroinflammation reflected by activated microglia and …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with
selective loss of upper and lower motor neurons. At sites of motor neuron injury …

Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disease
affecting primarily the upper and lower motor neurons. A common feature of all ALS cases is …