[HTML][HTML] Neutrophils: a subgroup of neglected immune cells in ALS
W Cao, D Fan - Frontiers in Immunology, 2023 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a chronic, progressive neurodegenerative disease
characterized by the loss of motor neurons. Dysregulated peripheral immunity has been …
characterized by the loss of motor neurons. Dysregulated peripheral immunity has been …
[HTML][HTML] Role of neuroinflammation in amyotrophic lateral sclerosis: cellular mechanisms and therapeutic implications
J Liu, F Wang - Frontiers in immunology, 2017 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects
upper motor neurons (MNs) comprising the corticospinal tract and lower MNs arising from …
upper motor neurons (MNs) comprising the corticospinal tract and lower MNs arising from …
Non-neuronal cells in amyotrophic lateral sclerosis—from pathogenesis to biomarkers
The prevailing motor neuron-centric view of amyotrophic lateral sclerosis (ALS)
pathogenesis could be an important factor in the failure to identify disease-modifying therapy …
pathogenesis could be an important factor in the failure to identify disease-modifying therapy …
[HTML][HTML] The role of immune-mediated alterations and disorders in ALS disease
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that leads
to neuronal death in the brain and spinal cord. Over the last decades, evidence has …
to neuronal death in the brain and spinal cord. Over the last decades, evidence has …
[HTML][HTML] Cellular therapy to target neuroinflammation in amyotrophic lateral sclerosis
F Rizzo, G Riboldi, S Salani, M Nizzardo… - Cellular and Molecular …, 2014 - Springer
Neurodegenerative disorders are characterized by the selective vulnerability and
progressive loss of discrete neuronal populations. Non-neuronal cells appear to significantly …
progressive loss of discrete neuronal populations. Non-neuronal cells appear to significantly …
Immunological drivers of amyotrophic lateral sclerosis
TF Gendron, L Petrucelli - Science translational medicine, 2023 - science.org
Amyotrophic lateral sclerosis (ALS), a devastating motor neuron disease involving complex
genetic and environmental factors, is associated with neuroinflammation. Preclinical and …
genetic and environmental factors, is associated with neuroinflammation. Preclinical and …
Interplay between immunity and amyotrophic lateral sclerosis: Clinical impact
Amyotrophic lateral sclerosis (ALS) is a debilitating and rapidly fatal neurodegenerative
disease. Despite decades of research and many new insights into disease biology over the …
disease. Despite decades of research and many new insights into disease biology over the …
Non‐neuronal cells in ALS: Role of glial, immune cells and blood‐CNS barriers
F Puentes, A Malaspina, JM Van Noort… - Brain …, 2016 - Wiley Online Library
Neurological dysfunction and motor neuron degeneration in amyotrophic lateral sclerosis
(ALS) is strongly associated with neuroinflammation reflected by activated microglia and …
(ALS) is strongly associated with neuroinflammation reflected by activated microglia and …
Immune-mediated mechanisms in the pathoprogression of amyotrophic lateral sclerosis
W Zhao, DR Beers, SH Appel - Journal of Neuroimmune Pharmacology, 2013 - Springer
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with
selective loss of upper and lower motor neurons. At sites of motor neuron injury …
selective loss of upper and lower motor neurons. At sites of motor neuron injury …
Peripheral monocytes are functionally altered and invade the CNS in ALS patients
L Zondler, K Müller, S Khalaji, C Bliederhäuser… - Acta …, 2016 - Springer
Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disease
affecting primarily the upper and lower motor neurons. A common feature of all ALS cases is …
affecting primarily the upper and lower motor neurons. A common feature of all ALS cases is …