It is currently accepted that adult tissues may develop and maintain their own stem cell
pools. Because of their higher safety profile, adult stem cells may represent an ideal …

This study examined whether mesenchymal stem cells (MSCs), which are stem cells
originated from embryonic mesoderm, are able to differentiate into functional hepatocyte …

The advances in stem cell science have promoted research on their use in liver regenerative
medicine. Beyond the demonstration of their ability to display metabolic functions in vitro …

Chronic liver diseases constitute a significant economic, social, and biomedical burden.
Among commonly adopted approaches, only organ transplantation can radically help …

Recent observations indicate that several stem cells can differentiate into hepatocytes; thus,
cell‐based therapy is a potential alternative to liver transplantation. The goal of the present …

Mesenchymal stem cells (MSCs) derived from bone marrow have been shown to
differentiate into hepatocytes, which would be an ideal resource for transplantation or …

Donor organ shortage is still the major obstacle for the clinical application of hepatocyte
transplantation in the treatment of liver diseases. However, generation of hepatocyte-like …

Background and aim: Mesenchymal stem cells from bone marrow (MSCs) may have the
potential to differentiate in vitro and in vivo into hepatocytes. We investigated whether …

The origin of liver cells from distinct bone marrow stem cells, eg, hematopoietic stem cells or
multipotent adult progenitor cells has been recently described using in vitro studies. Cell …

Alternative methods to whole liver transplantation require a suitable cell that can be
expanded to obtain sufficient numbers required for successful transplantation while …