Adult-derived human liver mesenchymal-like cells as a potential progenitor reservoir of hepatocytes?
It is currently accepted that adult tissues may develop and maintain their own stem cell
pools. Because of their higher safety profile, adult stem cells may represent an ideal …
pools. Because of their higher safety profile, adult stem cells may represent an ideal …
[PDF][PDF] In vitro hepatic differentiation of human mesenchymal stem cells
KD Lee, TKC Kuo, J Whang‐Peng, YF Chung… - …, 2004 - Wiley Online Library
This study examined whether mesenchymal stem cells (MSCs), which are stem cells
originated from embryonic mesoderm, are able to differentiate into functional hepatocyte …
originated from embryonic mesoderm, are able to differentiate into functional hepatocyte …
Adult human liver mesenchymal stem/progenitor cells participate in mouse liver regeneration after hepatectomy
The advances in stem cell science have promoted research on their use in liver regenerative
medicine. Beyond the demonstration of their ability to display metabolic functions in vitro …
medicine. Beyond the demonstration of their ability to display metabolic functions in vitro …
[HTML][HTML] Mesenchymal stem cells in the adult human liver: hype or hope?
IV Kholodenko, LK Kurbatov, RV Kholodenko… - Cells, 2019 - mdpi.com
Chronic liver diseases constitute a significant economic, social, and biomedical burden.
Among commonly adopted approaches, only organ transplantation can radically help …
Among commonly adopted approaches, only organ transplantation can radically help …
[PDF][PDF] Adipose tissue‐derived mesenchymal stem cells as a source of human hepatocytes
A Banas, T Teratani, Y Yamamoto, M Tokuhara… - …, 2007 - Wiley Online Library
Recent observations indicate that several stem cells can differentiate into hepatocytes; thus,
cell‐based therapy is a potential alternative to liver transplantation. The goal of the present …
cell‐based therapy is a potential alternative to liver transplantation. The goal of the present …
Spheroid formation and differentiation into hepatocyte-like cells of rat mesenchymal stem cell induced by co-culture with liver cells
Z Qihao, C Xigu, C Guanghui, Z Weiwei - DNA and cell biology, 2007 - liebertpub.com
Mesenchymal stem cells (MSCs) derived from bone marrow have been shown to
differentiate into hepatocytes, which would be an ideal resource for transplantation or …
differentiate into hepatocytes, which would be an ideal resource for transplantation or …
The generation of hepatocytes from mesenchymal stem cells and engraftment into murine liver
P Stock, S Brückner, S Ebensing, M Hempel… - Nature protocols, 2010 - nature.com
Donor organ shortage is still the major obstacle for the clinical application of hepatocyte
transplantation in the treatment of liver diseases. However, generation of hepatocyte-like …
transplantation in the treatment of liver diseases. However, generation of hepatocyte-like …
Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: engraftment and hepatocyte differentiation versus profibrogenic potential
LV Di Bonzo, I Ferrero, C Cravanzola, K Mareschi… - Gut, 2008 - gut.bmj.com
Background and aim: Mesenchymal stem cells from bone marrow (MSCs) may have the
potential to differentiate in vitro and in vivo into hepatocytes. We investigated whether …
potential to differentiate in vitro and in vivo into hepatocytes. We investigated whether …
Hepatocytic gene expression in cultured rat mesenchymal stem cells
C Lange, P Bassler, MV Lioznov, H Bruns… - Transplantation …, 2005 - Elsevier
The origin of liver cells from distinct bone marrow stem cells, eg, hematopoietic stem cells or
multipotent adult progenitor cells has been recently described using in vitro studies. Cell …
multipotent adult progenitor cells has been recently described using in vitro studies. Cell …
[PDF][PDF] Efficient generation of human hepatocytes by the intrahepatic delivery of clonal human mesenchymal stem cells in fetal sheep
J Chamberlain, T Yamagami, E Colletti, ND Theise… - …, 2007 - Wiley Online Library
Alternative methods to whole liver transplantation require a suitable cell that can be
expanded to obtain sufficient numbers required for successful transplantation while …
expanded to obtain sufficient numbers required for successful transplantation while …
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