Andrographolide attenuates complete freund's adjuvant induced arthritis via suppression of inflammatory mediators and pro-inflammatory cytokines
Ethnopharmacological relevance Traditional plant-derived medicines have enabled the
mankind in curing the wide spectrum of diseases throughout the ages. Andrographis …
mankind in curing the wide spectrum of diseases throughout the ages. Andrographis …
Andrographolide ameliorates oxidative stress, inflammation and histological outcome in complete Freund's adjuvant-induced arthritis
S Luo, H Li, J Liu, X Xie, Z Wan, Y Wang, Z Zhao… - Chemico-biological …, 2020 - Elsevier
Objectives As one of the main active ingredients of Chinese herbal medicine Andrographis
paniculate, andrographolide is used in domestic clinical treatment for respiratory infections …
paniculate, andrographolide is used in domestic clinical treatment for respiratory infections …
Andrographolide Benefits Rheumatoid Arthritis via Inhibiting MAPK Pathways
Z Li, J Tan, L Wang, Q Li - Inflammation, 2017 - Springer
Andrographolide (AD) is the main compound distributed in medicinal herb Andrographis
paniculata and exhibits anti-inflammatory activity. AD has been used for the treatment of …
paniculata and exhibits anti-inflammatory activity. AD has been used for the treatment of …
Inhibitory effects of andrographolide on activated macrophages and adjuvant-induced arthritis
Andrographolide, a diterpenoid lactone obtained from plant Andrographis paniculata, is
used in South Asian countries to relieve various inflammatory symptoms. To study the effects …
used in South Asian countries to relieve various inflammatory symptoms. To study the effects …
Inhibition of matrix metalloproteinases and inducible nitric oxide synthase by andrographolide in human osteoarthritic chondrocytes
Q Ding, X Ji, Y Cheng, Y Yu, Y Qi… - Modern rheumatology, 2013 - academic.oup.com
Objective The aim of this study was to investigate the effects of andrographolide on matrix
metalloproteinases (MMP) 1, 3, and 13 and inducible nitric oxide synthase (iNOS) in human …
metalloproteinases (MMP) 1, 3, and 13 and inducible nitric oxide synthase (iNOS) in human …
[HTML][HTML] Andrographolide attenuates synovial inflammation of osteoarthritis by interacting with tumor necrosis factor receptor 2 trafficking in a rat model
R Wang, J Li, X Xu, J Xu, H Jiang, Z Lv, R Wu… - Journal of Orthopaedic …, 2021 - Elsevier
Background Synovial inflammation plays a major role in the pathogenesis of osteoarthritis
(OA). This study investigated the effect of andrographolide (Andro) on synovial inflammation …
(OA). This study investigated the effect of andrographolide (Andro) on synovial inflammation …
Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264. 7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway
KC Lee, HH Chang, YH Chung, TY Lee - Journal of ethnopharmacology, 2011 - Elsevier
Ethnopharmacological significance Inflammation is involved in numerous diseases, such as
chronic inflammatory disease and cancer. Many plant products exhibit useful biological …
chronic inflammatory disease and cancer. Many plant products exhibit useful biological …
Andrographolide Inhibits Inflammatory Cytokines Secretion in LPS‐Stimulated RAW264.7 Cells through Suppression of NF‐κB/MAPK Signaling Pathway
Y Li, S He, J Tang, N Ding, X Chu… - Evidence‐Based …, 2017 - Wiley Online Library
Andrographolide, the main active component extracted from Andrographis paniculata (Burm.
f.) Wall. ex Nees, exerts anti‐inflammatory effects; however, the principal molecular …
f.) Wall. ex Nees, exerts anti‐inflammatory effects; however, the principal molecular …
[HTML][HTML] Andrographolide, a natural anti-inflammatory agent: An Update
X Li, W Yuan, J Wu, J Zhen, Q Sun, M Yu - Frontiers in pharmacology, 2022 - frontiersin.org
Botanicals have attracted much attention in the field of anti-inflammatory due to their good
pharmacological activity and efficacy. Andrographis paniculata is a natural plant ingredient …
pharmacological activity and efficacy. Andrographis paniculata is a natural plant ingredient …
Is there a future for andrographolide to be an anti-inflammatory drug? Deciphering its major mechanisms of action
Andrographis paniculata has long been part of the traditional herbal medicine system in
Asia and in Scandinavia. Andrographolide was isolated as a major bioactive constituent of …
Asia and in Scandinavia. Andrographolide was isolated as a major bioactive constituent of …