Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism
S Badawy, YQ Yang, Y Liu, MA Marawan… - Critical Reviews in …, 2021 - Taylor & Francis
Abstract Ciprofloxacin (CIP)(human use) and enrofloxacin (ENR)(veterinary use) are
synthetic anti-infectious medications that belong to the second generation of …
synthetic anti-infectious medications that belong to the second generation of …
[PDF][PDF] Ciprofloxacin increases hepatic and renal lipid hydroperoxides levels in mice
AI Weyers, LI Ugnia, HG Ovando, NB Gorla - Biocell, 2002 - pdfs.semanticscholar.org
Ciprofloxacin (CFX) is an effective and relatively safe antimicrobial used in a variety of
human infections. However, adverse drug reactions and positive results in genotoxic tests …
human infections. However, adverse drug reactions and positive results in genotoxic tests …
A proposed “steric-like effect” for the slowdown of enrofloxacin antibiotic metabolism by ciprofloxacin, and its mechanism
X Xu, Q Lu, Y Yang, MA Martínez, B Lopez-Torres… - Chemosphere, 2021 - Elsevier
The results of monitoring over the years have shown that the mixing and coexistence of
various low-level antibiotic residual pollutants has increased significantly, among which, the …
various low-level antibiotic residual pollutants has increased significantly, among which, the …
Microsomal metabolism of ciprofloxacin generates free radicals
A Gürbay, B Gonthier, D Daveloose, A Favier… - Free Radical Biology …, 2001 - Elsevier
Ciprofloxacin (CPFX) is a widely used fluoroquinolone antibiotic with a broad spectrum of
activity. However, clinical experience has shown a possible incidence of undesirable …
activity. However, clinical experience has shown a possible incidence of undesirable …
Ciprofloxacin cardiotoxicity and hepatotoxicity in humans and animals
E Adikwu, N Brambaifa - Pharmacology & Pharmacy, 2012 - eprints.go4mailburst.com
Ciprofloxacin is generally well tolerated; the most common adverse effects include gastro
intestinal tract, central nervous system and hematological system effects. Recently rising …
intestinal tract, central nervous system and hematological system effects. Recently rising …
Oxidative stress induced by fluoroquinolone enrofloxacin in zebrafish (Danio rerio) can be ameliorated after a prolonged exposure
P Sehonova, N Tokanova, N Hodkovicova… - Environmental …, 2019 - Elsevier
The purpose of our experiment was to evaluate the effect of enrofloxacin on
biotransformation, oxidative stress and mRNA expression of related genes in fish as a non …
biotransformation, oxidative stress and mRNA expression of related genes in fish as a non …
Responses of Cirrhinus mrigala to second‐generation fluoroquinolone (ciprofloxacin) toxicity: Assessment of antioxidants, tissue morphology, and inorganic ions
Ciprofloxacin drugs are a second‐generation fluoroquinolone highly prescribed medication
against various bacterial infections in human and aquaculture practices. These drugs are …
against various bacterial infections in human and aquaculture practices. These drugs are …
Ciprofloxacin-induced antibacterial activity is reversed by vitamin E and vitamin C
In the present study, we investigated the possible involvement of oxidative stress in
ciprofloxacin-induced cytotoxicity against several reference bacteria including …
ciprofloxacin-induced cytotoxicity against several reference bacteria including …
[HTML][HTML] Ciprofloxacin-induced antibacterial activity is atteneuated by pretreatment with antioxidant agents
Ciprofloxacin works through interfering with replication and transcription of bacterial DNA,
which leads to increased oxidative stress, and death of bacterial cells. Drugs with strong …
which leads to increased oxidative stress, and death of bacterial cells. Drugs with strong …
Long-term toxicity of fluoroquinolones: a comprehensive review
NHA Hussen, SH Qadir, HS Rahman… - Drug and Chemical …, 2023 - Taylor & Francis
Fluoroquinolones (FQs) are highly potent bactericidal antibiotics with broad-spectrum
activity against Gram-negative/positive bacteria. The Food and Drug Administration (FDA) …
activity against Gram-negative/positive bacteria. The Food and Drug Administration (FDA) …