Intermittent hypoxia, initially associated with adverse effects of sleep apnea, has now
metamorphosed into a module for improved sports performance. The regimen followed for …

Intermittent hypoxic training (IHT) is a discrete cost-effective method for improving athletic
performance and high altitude acclimatization. Unfortunately, IHT protocols widely vary in …

Increased oxidative stress, defined as an imbalance between prooxidants and antioxidants,
resulting in molecular damage and disruption of redox signaling, is associated with …

Various strategies can be employed to prevent and manage altitude illnesses, including
habituation, oxygenation, nutritional support, and medication. Nevertheless, the utilization of …

In recent years, the altitude acclimatization responses elicited by short-term intermittent
exposure to hypoxia have been subject to renewed attention. The main goal of short-term …

Inflammation is an adaptive response to both external and internal stimuli including
infection, trauma, surgery, ischemia-reperfusion, or malignancy. A number of studies …

It is well-established that different altitude training modalities can improve convective oxygen
(O2) transport capacity and physical fitness of athletes (Millet et al., 2010). Exercising in …

The key regulators of the transcriptional response to hypoxia and inflammation (hypoxia
inducible factor, HIF, and nuclear factor-kappa B, NF-κB, respectively) are evolutionarily …

Homeostasis between pro-oxidants and anti-oxidants is necessary for aerobic life, which if
perturbed and shifted towards pro-oxidants results in oxidative stress. It is generally agreed …

Hypoxia due to altitude diminishes performance and alters exercise oxidative stress
responses. While oxidative stress and exercise are well studied, the independent impact of …