Menstruation pulls the trigger for inflammation and pain in endometriosis

A Laux-Biehlmann, T d'Hooghe, TM Zollner - Trends in pharmacological …, 2015 - cell.com
Endometriosis is a chronic, hormone-dependent, inflammatory disease, characterized by the
presence and growth of endometrial tissue outside the uterine cavity. It affects 5–10% of the …

Neurogenic inflammation in the context of endometriosis—what do we know?

RV Velho, E Taube, J Sehouli, S Mechsner - International Journal of …, 2021 - mdpi.com
Endometriosis (EM) is an estrogen-dependent disease characterized by the presence of
epithelial, stromal, and smooth muscle cells outside the uterine cavity. It is a chronic and …

Pathophysiology and immune dysfunction in endometriosis

SH Ahn, SP Monsanto, C Miller… - BioMed research …, 2015 - Wiley Online Library
Endometriosis is an estrogen‐dependent, chronic, proinflammatory disease prevalent in
10% of women of reproductive age worldwide. Characterized by the growth of endometrium …

A lifelong impact on endometriosis: pathophysiology and pharmacological treatment

LH Chen, WC Lo, HY Huang, HM Wu - International Journal of Molecular …, 2023 - mdpi.com
Endometriosis is a chronic inflammatory disease associated with bothersome symptoms in
premenopausal women and is complicated with long-term systemic impacts in the post …

Pain in endometriosis

J Maddern, L Grundy, J Castro… - Frontiers in cellular …, 2020 - frontiersin.org
Endometriosis is a chronic and debilitating condition affecting∼ 10% of women.
Endometriosis is characterized by infertility and chronic pelvic pain, yet treatment options …

Pathogenesis of endometriosis: Interaction between Endocrine and inflammatory pathways

BG Patel, EE Lenk, DI Lebovic, Y Shu, J Yu… - Best practice & research …, 2018 - Elsevier
Despite an estimated prevalence of 11% in women and plausible historical descriptions
dating back to the 17th century, the etiology of endometriosis remains poorly understood …

Inflammatory mediators and pain in endometriosis: a systematic review

N Machairiotis, S Vasilakaki, N Thomakos - Biomedicines, 2021 - mdpi.com
Background: pain is one of the main symptoms of endometriosis and it has a deleterious
effect on a patients' personal and social life. To date, the clinical management of pain …

Pain and endometriosis

S Evans, G Moalem-Taylor, DJ Tracey - Pain, 2007 - Elsevier
Endometriosis is the commonest cause of chronic pelvic pain in women (Fauconnier and
Chapron, 2005). It is characterized by the presence of uterine endometrial tissue outside of …

Villainous role of estrogen in macrophage-nerve interaction in endometriosis

Y Liang, H Xie, J Wu, D Liu, S Yao - Reproductive Biology and …, 2018 - Springer
Endometriosis is a complex and heterogeneous disorder with unknown etiology.
Dysregulation of macrophages and innervation are important factors influencing the …

Emerging drug targets for endometriosis

MM Dolmans, J Donnez - Biomolecules, 2022 - mdpi.com
Endometriosis is a chronic inflammatory disease causing distressing symptoms and
requiring a life-long management strategy. The objective of this review is to evaluate …