We recently developed a therapeutic biopolymer composed of an elastin-like polypeptide
(ELP) fused to vascular endothelial growth factor (VEGF) and showed long-term …

Renovascular disease (RVD) induces renal microvascular (MV) rarefaction that drives
progressive kidney injury. In previous studies, we showed that renal vascular endothelial …

Elastin-like polypeptides (ELP) are versatile protein biopolymers used in drug delivery due
to their modular nature, allowing fusion of therapeutics and targeting agents. We previously …

Renal angioplasty and stenting (PTRAs) resolves renal artery stenosis, but inconsistently
improves renal function, possibly due to persistent parenchymal damage. We developed a …

Background: Chronic renovascular disease (RVD) can lead to a progressive loss of renal
function, and current treatments are inefficient. We designed a fusion of vascular endothelial …

Abstract Vascular Endothelial Growth Factor (VEGF), a key mediator of angiogenesis and
vascular repair, is reduced in chronic ischemic renal diseases, leading to microvascular …

Chronic kidney disease (CKD) universally associates with renal microvascular rarefaction
and inflammation, but whether a link exists between these 2 processes is unclear. We …

Therapeutic angiogenesis by vascular endothelial growth fact... : Current Opinion in
Nephrology and Hypertension Therapeutic angiogenesis by vascular endothelial growth …

Role of vascular endothelial growth factor in the regulation of angiogenesis. Compelling
evidence indicates that vascular endothelial growth factor (VEGF) is a fundamental regulator …

Renal microvascular (MV) damage and loss contribute to the progression of renal injury in
renovascular disease (RVD). Whether a targeted intervention in renal microcirculation could …