Extracellular matrix-based biomaterials and their influence upon cell behavior

MC Cramer, SF Badylak - Annals of biomedical engineering, 2020 - Springer
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

Biologic Scaffolds for Regenerative Medicine: Mechanisms of In vivo Remodeling

R Londono, SF Badylak - Annals of biomedical engineering, 2015 - Springer
Successful regenerative medicine strategies for functional tissue reconstruction include the
in situ placement of acellular materials composed of the extracellular matrix (ECM) or …

Extracellular matrix-based biomaterial scaffolds and the host response

JM Aamodt, DW Grainger - Biomaterials, 2016 - Elsevier
Extracellular matrix (ECM) collectively represents a class of naturally derived proteinaceous
biomaterials purified from harvested organs and tissues with increasing scientific focus and …

Biologic scaffolds

A Costa, JD Naranjo… - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix are
commonly used for the repair and functional reconstruction of injured and missing tissues …

Decellularized allogeneic and xenogeneic tissue as a bioscaffold for regenerative medicine: factors that influence the host response

SF Badylak - Annals of biomedical engineering, 2014 - Springer
Biologic scaffold materials composed of mammalian extracellular matrix (ECM) are prepared
by decellularization of source tissues harvested from either humans (allogeneic) or a variety …

Extracellular matrix as a biological scaffold material: Structure and function

SF Badylak, DO Freytes, TW Gilbert - Acta biomaterialia, 2009 - Elsevier
Biological scaffold materials derived from the extracellular matrix (ECM) of intact mammalian
tissues have been successfully used in a variety of tissue engineering/regenerative …

Inflammation-mediated matrix remodeling of extracellular matrix-mimicking biomaterials in tissue engineering and regenerative medicine

M Xu, T Su, X Jin, Y Li, Y Yao, K Liu, K Chen, F Lu… - Acta Biomaterialia, 2022 - Elsevier
Extracellular matrix (ECM)-mimicking biomaterials are considered effective tissue-
engineered scaffolds for regenerative medicine because of their biocompatibility …

Extracellular matrix as an inductive scaffold for functional tissue reconstruction

BN Brown, SF Badylak - Translational Research, 2014 - Elsevier
The extracellular matrix (ECM) is a meshwork of both structural and functional proteins
assembled in unique tissue-specific architectures. The ECM both provides the mechanical …

Leveraging “raw materials” as building blocks and bioactive signals in regenerative medicine

AN Renth, MS Detamore - Tissue Engineering Part B: Reviews, 2012 - liebertpub.com
Components found within the extracellular matrix (ECM) have emerged as an essential
subset of biomaterials for tissue engineering scaffolds. Collagen, glycosaminoglycans …

Solubilized extracellular matrix bioscaffolds derived from diverse source tissues differentially influence macrophage phenotype

JL Dziki, DS Wang, C Pineda, BM Sicari… - … research Part A, 2017 - Wiley Online Library
The host response to biomaterials is a critical determinant of their success or failure in tissue‐
repair applications. Macrophages are among the first responders in the host response to …