[HTML][HTML] Afamin—A pleiotropic glycoprotein involved in various disease states

H Dieplinger, B Dieplinger - Clinica Chimica Acta, 2015 - Elsevier
The human glycoprotein afamin was discovered as the fourth member of the albumin gene
family. Despite intense research over the last 20 years, our knowledge of afamin's …

[HTML][HTML] Analytical characterization and clinical evaluation of an enzyme-linked immunosorbent assay for measurement of afamin in human plasma

B Dieplinger, M Egger, C Gabriel, W Poelz… - Clinica chimica acta, 2013 - Elsevier
Background Comparative proteomics has recently identified afamin, the newest member of
the albumin gene family, as a potential biomarker for ovarian cancer. The aim of this study …

Plasma concentrations of afamin are associated with the prevalence and development of metabolic syndrome

F Kronenberg, B Kollerits, S Kiechl… - Circulation …, 2014 - Am Heart Assoc
Background—Afamin is a human plasma vitamin E–binding glycoprotein primarily
expressed in the liver and secreted into the bloodstream. Because little is known about …

[HTML][HTML] Serum afamin a novel marker of increased hepatic lipid content

T Kurdiova, M Balaz, Z Kovanicova… - Frontiers in …, 2021 - frontiersin.org
Aim Afamin is a liver-produced glycoprotein, a potential early marker of metabolic syndrome.
Here we investigated regulation of afamin in a course of the metabolic disease development …

Proteomic profiling identifies afamin as a potential biomarker for ovarian cancer

D Jackson, RA Craven, RC Hutson, I Graze, P Lueth… - Clinical cancer …, 2007 - AACR
Purpose: To discover and validate serum glycoprotein biomarkers in ovarian cancer using
proteomic-based approaches. Experimental Design: Serum samples from a “discovery set” …

Afamin and apolipoprotein A-IV: novel protein markers for ovarian cancer

H Dieplinger, DP Ankerst, A Burges, M Lenhard… - … Biomarkers & Prevention, 2009 - AACR
Comparative proteomics identified the vitamin E-binding plasma protein afamin as a
potential novel tumor marker for ovarian cancer. In addition, we observed in a previous small …

Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression

L Jerkovic, AF Voegele, S Chwatal… - Journal of proteome …, 2005 - ACS Publications
Hydrophobic vitamins are transported in human plasma and extravascular fluids by carrier
proteins. No specific protein has been described so far for vitamin E, which plays a crucial …

[HTML][HTML] Afamin levels and their correlation with oxidative and lipid parameters in non-diabetic, obese patients

I Juhász, S Ujfalusi, I Seres, H Lőrincz, VE Varga… - Biomolecules, 2022 - mdpi.com
Background: Afamin is a liver-produced bioactive protein and features α-and γ-tocopherol
binding sites. Afamin levels are elevated in metabolic syndrome and obesity and correlate …

Plasma concentrations of afamin are associated with prevalent and incident type 2 diabetes: a pooled analysis in more than 20,000 individuals

B Kollerits, C Lamina, C Huth, P Marques-Vidal… - Diabetes …, 2017 - Am Diabetes Assoc
OBJECTIVE The human vitamin E–binding glycoprotein afamin is primarily expressed in the
liver and has been associated with prevalent and incident metabolic syndrome. These data …

[HTML][HTML] The vitamin E-binding protein afamin increases in maternal serum during pregnancy

M Hubalek, H Buchner, MG Mörtl, D Schlembach… - Clinica chimica acta, 2014 - Elsevier
Background Afamin is a liver-derived plasma glycoprotein with vitamin E-binding properties
and a putative function in fertility. This study evaluated serum afamin concentrations during …