NY-ESO-1 based immunotherapy of cancer: current perspectives
R Thomas, G Al-Khadairi, J Roelands… - Frontiers in …, 2018 - frontiersin.org
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-
testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit …
testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit …
Current advances in cancer vaccines targeting NY-ESO-1 for solid cancer treatment
H Zhou, Y Ma, F Liu, B Li, D Qiao, P Ren… - Frontiers in …, 2023 - frontiersin.org
New York-esophageal cancer 1 (NY-ESO-1) belongs to the cancer testis antigen (CTA)
family, and has been identified as one of the most immunogenic tumor-associated antigens …
family, and has been identified as one of the most immunogenic tumor-associated antigens …
Unleashing the immune response to NY-ESO-1 cancer testis antigen as a potential target for cancer immunotherapy
Abstract Introduction Cancer Immunotherapy has recently emerged as a promising and
effective modality to treat different malignancies. Antigenic profiling of cancer tissues and …
effective modality to treat different malignancies. Antigenic profiling of cancer tissues and …
Directions in the immune targeting of cancer: Lessons learned from the cancer‐testis Ag NY‐ESO‐1
Since the early 1990s, numerous cancer Ag have been defined and for a handful of these
there is now some clinical experience, which has made it possible to assess their value as …
there is now some clinical experience, which has made it possible to assess their value as …
NY‐ESO‐1: review of an immunogenic tumor antigen
S Gnjatic, H Nishikawa, AA Jungbluth, AO Güre… - Advances in cancer …, 2006 - Elsevier
In the 9 years since its discovery, cancer‐testis antigen NY‐ESO‐1 has made one of the
fastest transitions from molecular, cellular, and immunological description to vaccine and …
fastest transitions from molecular, cellular, and immunological description to vaccine and …
Immune targets and neoantigens for cancer immunotherapy and precision medicine
RF Wang, HY Wang - Cell research, 2017 - nature.com
Harnessing the immune system to eradicate malignant cells is becoming a most powerful
new approach to cancer therapy. FDA approval of the immunotherapy-based drugs …
new approach to cancer therapy. FDA approval of the immunotherapy-based drugs …
NY-ESO-1 119–143 is a promiscuous major histocompatibility complex class II T-helper epitope recognized by Th1-and Th2-type tumor-reactive CD4+ T cells
HM Zarour, B Maillere, V Brusic, K Coval, E Williams… - Cancer research, 2002 - AACR
The NY-ESO-1 gene product is expressed by a range of human tumors and is recognized by
antibodies from sera of cancer patients with NY-ESO-1-expressing tumors. The NY-ESO-1 …
antibodies from sera of cancer patients with NY-ESO-1-expressing tumors. The NY-ESO-1 …
Immune responses to tumour antigens: implications for antigen specific immunotherapy of cancer
D Jäger, E Jäger, A Knuth - Journal of clinical pathology, 2001 - jcp.bmj.com
Tumour associated antigens recognised by cellular or humoral effectors of the immune
system are potential targets for antigen specific cancer immunotherapy. Different categories …
system are potential targets for antigen specific cancer immunotherapy. Different categories …
NY-ESO-1 Protein Formulated in ISCOMATRIX Adjuvant Is a Potent Anticancer Vaccine Inducing Both Humoral and CD8+ T-Cell-Mediated Immunity and Protection against NY …
E Maraskovsky, S Sjölander, DP Drane… - Clinical cancer …, 2004 - AACR
Abstract NY-ESO-1 is a 180 amino-acid human tumor antigen expressed by many different
tumor types and belongs to the family of “cancer-testis” antigens. In humans, NY-ESO-1 is …
tumor types and belongs to the family of “cancer-testis” antigens. In humans, NY-ESO-1 is …
Identification of Ny-Eso-1 Epitopes Presented by Human Histocompatibility Antigen (Hla)-Drb4*0101–0103 and Recognized by Cd4+T Lymphocytes of Patients with …
E Jäger, D Jäger, J Karbach, YT Chen… - The Journal of …, 2000 - rupress.org
NY-ESO-1 is a member of the cancer-testis family of tumor antigens that elicits strong
humoral and cellular immune responses in patients with NY-ESO-1–expressing cancers …
humoral and cellular immune responses in patients with NY-ESO-1–expressing cancers …
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