The outstanding acuity of the mammalian ear relies on cochlear amplification, an active
mechanism based on the electromotility (eM) of outer hair cells. eM is a piezoelectric …

Prestin is a member of the SLC26 family of anion transporters that has evolved to serve as a
molecular motor in outer hair cells (OHCs) of the mammalian inner ear. The protein is …

Prestin, the motor protein of cochlear outer hair cells, was identified 14 years ago. Prestin-
based outer hair cell motility is responsible for the exquisite sensitivity and frequency …

Prestin, a transporter‐like protein of the SLC26A family, acts as a piezoelectric transducer
that mediates the fast electromotility of outer hair cells required for cochlear amplification …

Hearing involves two fundamental processes: mechano-electrical transduction and signal
amplification. Despite decades of studies, the molecular bases for both remain elusive …

The mammalian outer hair cell (OHC) protein prestin (Slc26a5) differs from other Slc26
family members due to its unique piezoelectric-like property that drives OHC electromotility …

How proteins evolve new functionality is an important question in biology; prestin
(SLC26A5) is a case in point. Prestin drives outer hair cell somatic motility and amplifies …

Outer hair cells boost auditory performance in mammals. This amplification relies on an
expansive array of intramembranous molecular motors, identified as prestin, that drive …

Prestin, a member of the SLC26A family of anion transporters, is a polytopic membrane
protein found in outer hair cells (OHCs) of the mammalian cochlea. Prestin is an essential …

Abstract Prestin (SLC26a5) is an integral membrane motor protein in outer hair cells (OHC)
that underlies cochlear amplification. As a voltage-dependent protein, it relies on intrinsic …