Early tubular alterations were studied in 53 children with insulin-dependent diabetes
mellitus (IDDM), 32 of whom were followed at regular 6-monthly intervals for 3 years. The …

The urinary extraction of albumin, retinol binding protein, and N-acetyl-beta-D-
glucosaminidase were studied in 60 children with insulin dependent diabetes mellitus and …

The nature of microproteinuria in the early years of insulin-dependent diabetes was
investigated in a cross sectional study of 80 children with insulin-dependent diabetes and 40 …

The glomerular and proximal tubular function of the diabetic kidney was investigated. The
urinary excretion (relative clearance) of albumin, a marker of glomerular function, and retinol …

Renal function has been evaluated in 45 diabetic children (age 12.5±4 years) with a mean
diabetes duration of 4.9±3.5 years. Glomerular filtration rate (GFR; inulin and creatinine …

The relationship of early retinal changes and subclinical proteinuria to duration and
metabolicregulation of insulin-dependent diabetes was studied in 67 children. Retinopathy …

The objective of this study was to determine the prevalence of stages of diabetic
nephropathy, defined by the albumin/creatinine ratio (AC ratio) in repeated measurements in …

Urinary albumin excretion (UAE) was determined by radioimmunoassay in two 24 h urine
collections from 125 diabetic children and adolescents and from 71 normal children …

The urinary excretion of two low-molecular-weight proteins (beta 2-microglobulin and retinol-
binding protein) was measured in 12 insulin-dependent diabetic patients with persistent …

In 109 patients with insulin-dependent diabetes mellitus (IDDM), we measured the urinary
excretion of albumin, the low molecular weight proteins (LMWP) retinol-binding protein …