Inflammatory cell phenotypes in AAAs: their role and potential as targets for therapy
MA Dale, MK Ruhlman, BT Baxter - … , thrombosis, and vascular …, 2015 - Am Heart Assoc
Abdominal aortic aneurysms (AAAs) are characterized by chronic inflammatory cell
infiltration. AAA is typically an asymptomatic disease and caused≈ 15 000 deaths annually …
infiltration. AAA is typically an asymptomatic disease and caused≈ 15 000 deaths annually …
Inflammation in abdominal aortic aneurysms: cellular infiltrate and cytokine profiles
MJ Eagleton - Vascular, 2012 - journals.sagepub.com
Abdominal aortic aneurysm (AAA) pathogenesis occurs as a result of the altered
homeostasis of the aortic vessel wall structural proteins. This results in weakening, and …
homeostasis of the aortic vessel wall structural proteins. This results in weakening, and …
Abdominal aortic aneurysm: roles of inflammatory cells
Z Yuan, Y Lu, J Wei, J Wu, J Yang, Z Cai - Frontiers in immunology, 2021 - frontiersin.org
Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …
Monocytes and macrophages in abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …
Abdominal aortic aneurysms: an autoimmune disease?
VP Jagadesham, DJA Scott, SR Carding - Trends in molecular medicine, 2008 - cell.com
Abdominal aortic aneurysms (AAAs) are a multifactorial degenerative vascular disorder. One
of the defining features of the pathophysiology of aneurysmal disease is inflammation …
of the defining features of the pathophysiology of aneurysmal disease is inflammation …
Inflammation and cellular immune responses in abdominal aortic aneurysms
K Shimizu, RN Mitchell, P Libby - Arteriosclerosis, thrombosis, and …, 2006 - Am Heart Assoc
Expansion and rupture of abdominal aortic aneurysms (AAA) result in high morbidity and
mortality rates. Like stenotic atherosclerotic lesions, AAA accumulate inflammatory cells, but …
mortality rates. Like stenotic atherosclerotic lesions, AAA accumulate inflammatory cells, but …
Immune and inflammatory mechanisms of abdominal aortic aneurysm
AC Marquez-Sanchez, EK Koltsova - Frontiers in immunology, 2022 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-
mediated infiltration and a destruction of the aortic wall during AAA development plays …
mediated infiltration and a destruction of the aortic wall during AAA development plays …
Single-cell RNA sequencing reveals heterogeneity of vascular cells in early stage murine abdominal aortic aneurysm—brief report
Objective: Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease
characterized by smooth muscle cell depletion, ECM (extracellular matrix) degradation, and …
characterized by smooth muscle cell depletion, ECM (extracellular matrix) degradation, and …
Modulation of immune‐inflammatory responses in abdominal aortic aneurysm: Emerging molecular targets
H Li, S Bai, Q Ao, X Wang, X Tian, X Li… - Journal of …, 2018 - Wiley Online Library
Abdominal aortic aneurysm (AAA), a deadly vascular disease in human, is a chronic
degenerative process of the abdominal aorta. In this process, inflammatory responses and …
degenerative process of the abdominal aorta. In this process, inflammatory responses and …
T cells are dominant population in human abdominal aortic aneurysms and their infiltration in the perivascular tissue correlates with disease severity
A Sagan, TP Mikolajczyk, W Mrowiecki… - Frontiers in …, 2019 - frontiersin.org
Abdominal Aortic Aneurysm (AAA) is a major cause of cardiovascular mortality. Adverse
changes in vascular phenotype act in concert with chronic inflammation to promote AAA …
changes in vascular phenotype act in concert with chronic inflammation to promote AAA …