Ventricular arrhythmias are a major cause of sudden death, which accounts for
approximately half of cardiac mortality. The His–Purkinje system is composed of specialized …

There has been growing evidence that the Purkinje network plays a pivotal role in both the
initiation and perpetuation of ventricular fibrillation (VF). A triggering ventricular premature …

Of the monomorphic ventricular tachycardias, there are 4 specific tachycardias related to the
Purkinje system: 1) idiopathic verapamil-sensitive fascicular ventricular tachycardia (FVT); 2) …

Purkinje cells are specialized for rapid propagation in the heart. Furthermore, Purkinje fibers
as the source as well as the perpetuator of arrhythmias is a familiar finding. This is not …

Purkinje‐related monomorphic ventricular tachycardias (VTs) can be classified into four
distinct groups:(1) verapamil‐sensitive left fascicular VT,(2) Purkinje fiber‐mediated VT post …

Although a plethora of earlier studies focused on the histology and action potential
characteristics of Purkinje fibers, only recently has the His-Purkinje system been found to …

Cardiac Purkinje fibers, due to their unique anatomical location, cell structure and
electrophysiologic characteristics, play an important role in cardiac conduction and …

Rationale: The Purkinje fiber network has been proposed as the source of arrhythmogenic
Ca2+ release events in catecholaminergic polymorphic ventricular tachycardia (CPVT), yet …

The His–Purkinje conduction system initiates the normal excitation of the ventricles and is a
major component of the specialized conduction system of the heart. Abnormalities and …

Objective and methods: In this study, we investigated whether Ca2+ transients are altered in
Purkinje cell aggregates dispersed from the subendocardium overlying the infarcted zone of …