The nature and neurobiology of fear and anxiety: State of the science and opportunities for accelerating discovery

SE Grogans, E Bliss-Moreau, KA Buss, LA Clark… - Neuroscience & …, 2023 - Elsevier
Fear and anxiety play a central role in mammalian life, and there is considerable interest in
clarifying their nature, identifying their biological underpinnings, and determining their …

Translating across circuits and genetics toward progress in fear-and anxiety-related disorders

KJ Ressler - American Journal of Psychiatry, 2020 - Am Psychiatric Assoc
Anxiety and fear-related disorders are common and disabling, and they significantly
increase risk for suicide and other causes of morbidity and mortality. However, there is …

[图书][B] Handbook of anxiety and fear

DC Blanchard, G Griebel, DJ Nutt - 2011 - books.google.com
This Handbook brings together and integrates comprehensively the core approaches to fear
and anxiety. Its four sections: Animal models; neural systems; pharmacology; and clinical …

The biology of fear-and anxiety-related behaviors

T Steimer - Dialogues in clinical neuroscience, 2002 - Taylor & Francis
Anxiety is a psychological, physiological, and behavioral state induced in animals and
humans by a threat to well-being or survival, either actual or potential. It is characterized by …

Using neuroscience to help understand fear and anxiety: a two-system framework

JE LeDoux, DS Pine - American journal of psychiatry, 2016 - Am Psychiatric Assoc
Tremendous progress has been made in basic neuroscience in recent decades. One area
that has been especially successful is research on how the brain detects and responds to …

A return to the psychiatric dark ages with a two-system framework for fear

MS Fanselow, ZT Pennington - Behaviour research and therapy, 2018 - Elsevier
The past several decades has seen considerable progress in our understanding of the
neurobiology of fear and anxiety. These advancements were spurred on by envisioning fear …

The psychobiology of anxiety

J Kim, J Gorman - Clinical Neuroscience Research, 2005 - Elsevier
When the basic survival mechanism of fear goes awry, the result is often an anxiety disorder.
The activation and modulation of the fear system in animals and humans has thus been an …

Neurocognitive mechanisms of anxiety: an integrative account

SJ Bishop - Trends in cognitive sciences, 2007 - cell.com
Anxiety can be hugely disruptive to everyday life. Anxious individuals show increased
attentional capture by potential signs of danger, and interpret expressions, comments and …

[HTML][HTML] Are fear and anxiety truly distinct?

L Daniel-Watanabe, PC Fletcher - Biological psychiatry global open science, 2022 - Elsevier
Fear and anxiety are largely seen as separate entities, a distinction that inspires and shapes
basic and clinical research. Evidence for this distinction has a rich translational base and …

[PDF][PDF] Fear and anxiety

A Öhman - Handbook of emotions, 2008 - academia.edu
Fear is a ubiquitous experience among humankind that can be traced back to a distant
mammalian heritage. Recent world events, with terrorist attacks randomly striking innocent …