Lung cancer is a leading cause of global cancer deaths. Na/K-ATPase has been studied as
a target for cancer treatment. Cardiotonic steroids (CS) trigger intracellular signalling upon …

Cells contain a large pool of nonpumping Na/K-ATPase that participates in signal
transduction. Here, we show that the expression of α1 Na/K-ATPase is significantly reduced …

Introduction: Na/K-ATPase is a heterodimeric transmembrane protein that regulates
neuronal signaling, ion homeostasis, muscle contraction and substrate transportation …

Diminished Na, K-ATPase expression has been reported in several carcinomas and has
been linked to tumor progression. However, few studies have determined whether Na, K …

The sodium pump, Na+/K+-ATPase, could be an important target for the development of
anticancer drugs as it serves as a versatile signal transducer, plays a key role in cell …

Background: The sodium pump (Na+/K+-ATPase) could be a target for the development of
anticancer drugs as it serves as a signal transducer, it is a player in cell adhesion and its …

Sodium potassium pump (Na+/K+ ATPase) is a transmembrane protein complex found in all
higher eukaryotes acting as a key energy-consuming pump maintaining ionic and osmotic …

The Na, K-ATPase classically serves as an ion pump creating an electrochemical gradient
across the plasma membrane that is essential for transepithelial transport, nutrient uptake …

Abstract Na/K-ATPase (NKA) is a p-type transmembrane enzyme formed by three different
subunits (α, β, and γ gamma). Primarily responsible for transporting sodium and potassium …

With an overall 5 year survival rate as low as 15% for non‐small cell lung cancer (NSCLC),
even with surgical intervention and the use of newer molecules in adjuvant chemotherapy …