Sepsis‐induced diaphragmatic inflammation has been associated with respiratory failure,
but the role of chemokines in this process has not been evaluated. Here we sought to study …

Background: Sepsis-induced diaphragmatic force loss and failure are associated with an
increased exposure of the muscle to proinflammatory mediators. Objectives: Our objectives …

Chemokine receptors are important for recruiting leukocytes to sites of infection and may
contribute to immune cell activation. The present study investigated the role of the …

Acute respiratory distress syndrome (ARDS) consists of uncontrolled inflammation that
causes hypoxemia and reduced lung compliance. Since it is a complex process, not all …

Lung contusion (LC), commonly observed in patients with thoracic trauma is a leading risk
factor for development of acute lung injury/acute respiratory distress syndrome. Previously …

Rationale: Sepsis is defined as a systemic inflammatory response to infection, which in its
severe form is associated with multiple organ dysfunction syndrome (MODS). The precise …

The host response to Gram-negative LPS is characterized by an influx of inflammatory cells
into host tissues, which is mediated, in part, by localized production of chemokines. The …

The CC chemokine monocyte chemotactic protein 1 (JE/MCP-1) is a key cytokine for lung
monocyte recruitment, and may be detected in high levels in the alveolar space in lung …

CC chemokine receptor (CCR) 4, a high affinity receptor for the CC chemokines thymus and
activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC), is …

Abstract Macrophage-derived chemokine (MDC), a recently identified CC chemokine, has
been regarded to be involved in chronic inflammation and dendritic cell and lymphocyte …