Tau, a neuronal protein involved in neurodegenerative disorders such as Alzheimer
disease, which is primarily described as a microtubule-associated protein, has also been …

Nucleic acid protection is a substantial challenge for neurons, which are continuously
exposed to oxidative stress in the brain. Neurons require powerful mechanisms to protect …

Tau is known for its pathological role in neurodegenerative diseases, including Alzheimer's
disease (AD) and other tauopathies. Tau is found in many subcellular compartments such as …

The microtubule-associated protein tau is involved in a number of neurodegenerative
disorders, including Alzheimer's disease. Previous studies have linked oxidative stress and …

Tau protein, found in both neuronal and non-neuronal cells, forms aggregates in neurons
that constitutes one of the hallmarks of Alzheimer's disease (AD). For nearly four decades …

DNA double-strand break (DSB) is the most severe form of DNA damage and accumulates
with age, in which cytoskeletal proteins are polymerized to repair DSB in dividing cells …

Truncation of tau protein and oxidative stress have been implicated as important
pathogenetic events in tauopathies including Alzheimer's disease (AD). We have generated …

Exposure to chronic stress is frequently accompanied by cognitive and affective disorders in
association with neurostructural adaptations. Chronic stress was previously shown to trigger …

Tau is a neuronal microtubule associated protein whose main biological functions are to
promote microtubule self-assembly by tubulin and to stabilize those already formed. Tau …

Tau, an important microtubule associated protein, has been found to bind to DNA, and to be
localized in the nuclei of both neurons and some non-neuronal cells. Here, using …