Background Successful treatment of infectious bone defect remains a major challenge in the
orthopaedic field. At present, the conventional treatment for infectious bone defects is …

The clinical treatment of infectious bone defects is difficult and time-consuming due to the
coexistence of infection and bone defects, and the simultaneous control of infection and …

In clinical practice, challenges remain in the treatment of large infected bone defects. Bone
tissue engineering scaffolds with good mechanical properties and antibiotic-controlled …

In the field of orthopedics, an infected bone defect is a refractory disease accompanied by
bone infection and defects as well as aggravated circulation. There are currently no …

The effective management of osteomyelitis remains extremely challenging due to the
difficulty associated with treating bone defects, the high probability of recurrence, the …

Chronic osteomyelitis is mostly caused by bacteria such as S. aureus, and is often treated
with oral antibiotics or injections to suppress the bacteria. In severe cases, however, surgical …

Repair and regeneration of large bone defects is still a challenge, especially for defects
which are the irregular and complex. Three-dimension (3D) printing, as an advanced …

Infectious bone defects present a major challenge in the clinical setting currently. In order to
address this issue, it is imperative to explore the development of bone tissue engineering …

Infection is one of the pivotal causes of nonunion in large bone defect after trauma or tumor
resection. Three-dimensional (3D) composite scaffold with multifunctional-therapeutic …

Bone infection is a feared complication following surgery or trauma that remains as an
extremely difficult disease to deal with. So far, the outcome of therapy could be improved …