MicroRNAs: Harbingers and shapers of periodontal inflammation

X Luan, X Zhou, P Fallah, M Pandya, H Lyu… - Seminars in cell & …, 2022 - Elsevier
Periodontal disease is an inflammatory reaction of the periodontal tissues to oral pathogens.
In the present review we discuss the intricate effects of a regulatory network of gene …

MicroRNAs and immunity in periodontal health and disease

X Luan, X Zhou, A Naqvi, M Francis, D Foyle… - International Journal of …, 2018 - nature.com
MicroRNAs (miRNAs) are critical regulators of the host immune and inflammatory response
against bacterial pathogens. In the present review, we discuss target genes, target gene …

MicroRNAs and periodontal homeostasis

X Luan, X Zhou, J Trombetta-eSilva… - Journal of dental …, 2017 - journals.sagepub.com
MicroRNAs (miRNAs) are a group of small RNAs that control gene expression in all aspects
of eukaryotic life, primarily through RNA silencing mechanisms. The purpose of the present …

The role of microRNA in periodontal tissue: A review of the literature

RA Irwandi, A Vacharaksa - Archives of Oral Biology, 2016 - Elsevier
MicroRNAs (miRNAs) bind at the 3′ UTR of their target mRNA to induce gene silencing.
Through this mechanism, number of biological pathways implicated in developmental …

MicroRNAs regulate cytokine responses in gingival epithelial cells

SCY Chen, C Constantinides, M Kebschull… - Infection and …, 2016 - Am Soc Microbiol
MicroRNAs (miRNAs) have been established as key regulators of various biological
processes with possible involvement in the pathobiology of periodontal disease. Expanding …

The emerging role of microRNA in periodontitis: pathophysiology, clinical potential and future molecular perspectives

S Santonocito, A Polizzi, G Palazzo, G Isola - International Journal of …, 2021 - mdpi.com
During the last few decades, it has been established that messenger ribonucleic acid
(mRNA) transcription does not inevitably lead to protein translation, but there are numerous …

[HTML][HTML] MicroRNAs and periodontal disease: a qualitative systematic review of human studies

P Micó-Martínez, PJ Almiñana-Pastor… - Journal of periodontal …, 2021 - ncbi.nlm.nih.gov
Purpose MicroRNAs (miRNAs) are epigenetic post-transcriptional regulators that modulate
gene expression and have been identified as biomarkers for several diseases, including …

miR‐584 Expressed in Human Gingival Epithelial Cells Is Induced by Porphyromonas gingivalis Stimulation and Regulates Interleukin‐8 Production via Lactoferrin …

K Ouhara, IJ Savitri, T Fujita, M Kittaka… - Journal of …, 2014 - Wiley Online Library
Background: MicroRNAs (miRNAs) are short, non‐coding RNAs that are involved in post‐
transcriptional regulation of gene expression. Differential miRNA expression in innate and …

[HTML][HTML] MicroRNAs: emerging players in apical periodontitis

Z Shen, RM Silva - Journal of Applied Oral Science, 2021 - SciELO Brasil
Apical periodontitis is an inflammatory disorder of periradicular tissues developed from
endodontic infections. Understanding its pathophysiology and the underlying molecular …

MicroRNAs and their target genes in gingival tissues

C Stoecklin-Wasmer, P Guarnieri… - Journal of dental …, 2012 - journals.sagepub.com
To gain insights into the in vivo function of miRNAs in the context of periodontitis, we
examined the occurrence of miRNAs in healthy and diseased gingival tissues and validated …