Precisely inhibiting excessive intestinal epithelial cell apoptosis to efficiently treat inflammatory bowel disease with oral pifithrin‐α embedded nanomedicine (OPEN)
M Wang, Q Huang, M Liu, T Zhao, X Song… - Advanced …, 2023 - Wiley Online Library
The increased incidence of inflammatory bowel disease (IBD) has seriously affected the life
quality of patients. IBD develops due to excessive intestinal epithelial cell (IEC) apoptosis …
quality of patients. IBD develops due to excessive intestinal epithelial cell (IEC) apoptosis …
Genistein-derived ROS-responsive nanoparticles relieve colitis by regulating mucosal homeostasis
W Fan, S Zhang, Y Wu, T Lu, J Liu, X Cao… - … Applied Materials & …, 2021 - ACS Publications
Disruption of intestinal homeostasis is an important event in the development of
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …
A proresolving peptide nanotherapy for site‐specific treatment of inflammatory bowel disease by regulating proinflammatory microenvironment and gut microbiota
C Li, Y Zhao, J Cheng, J Guo, Q Zhang… - Advanced …, 2019 - Wiley Online Library
The incidence and prevalence of inflammatory bowel disease (IBD) increases steadily
worldwide. There is an urgent need for effective and safe IBD therapies. Accelerated …
worldwide. There is an urgent need for effective and safe IBD therapies. Accelerated …
The progression of inorganic nanoparticles and natural products for inflammatory bowel disease
There is a growing body of evidence indicating a close association between inflammatory
bowel disease (IBD) and disrupted intestinal homeostasis. Excessive production of reactive …
bowel disease (IBD) and disrupted intestinal homeostasis. Excessive production of reactive …
Ultrathin hafnium disulfide atomic crystals with ROS-scavenging and colon-targeting capabilities for inflammatory bowel disease treatment
The exciting success of NBTXR3 in the clinic has triggered a tumult of activities in the design
and development of hafnium-based nanoparticles. However, due to the concerns of …
and development of hafnium-based nanoparticles. However, due to the concerns of …
Emerging nanomedicine and prodrug delivery strategies for the treatment of inflammatory bowel disease
M Sun, W Ban, H Ling, X Yu, Z He, Q Jiang… - Chinese Chemical …, 2022 - Elsevier
Inflammatory bowel disease (IBD) is a chronic and recurrent disease of the gastrointestinal
tract, mainly including Crohn's disease (CD) and ulcerative colitis (UC). However, current …
tract, mainly including Crohn's disease (CD) and ulcerative colitis (UC). However, current …
Rational design of orally administered cascade nanozyme for inflammatory bowel disease therapy
Y Yu, X Zhao, X Xu, C Cai, X Tang, Q Zhang… - Advanced …, 2023 - Wiley Online Library
Inflammatory bowel disease (IBD) affects millions of individuals worldwide annually. Enteric
reactive oxygen species (ROS) play critical roles in the physiology and pathology of IBD …
reactive oxygen species (ROS) play critical roles in the physiology and pathology of IBD …
Reactive Oxygen Species‐Activated CO Versatile Nanomedicine with Innate Gut Immune and Microbiome Remodeling Effects for Treating Inflammatory Bowel …
Y Zeng, M Fan, Q Zhou, D Chen, T Jin… - Advanced Functional …, 2023 - Wiley Online Library
Abnormal activation of the gut mucosal immune system and a highly dysregulated gut
microbiota play essential roles in the progression of inflammatory bowel disease (IBD). The …
microbiota play essential roles in the progression of inflammatory bowel disease (IBD). The …
ROS Scavenging and inflammation-directed polydopamine nanoparticles regulate gut immunity and flora therapy in inflammatory bowel disease
M Bao, K Wang, J Li, Y Li, H Zhu, M Lu, Y Zhang… - Acta Biomaterialia, 2023 - Elsevier
Dysfunction of the intestinal mucosal immune system and dysbiosis of the intestinal
microflora can induce inflammatory bowel disease. However, drug-mediated clinical …
microflora can induce inflammatory bowel disease. However, drug-mediated clinical …
Nanoprobiotics for remolding the pro-inflammatory microenvironment and microbiome in the treatment of colitis
J Li, M Sun, L Liu, W Yang, A Sun, J Yu, D Liu… - Nano Letters, 2023 - ACS Publications
Despite the great progress of current bacterially based biotherapeutics, their unsatisfying
efficacy and underlying safety problems have limited their clinical application. Herein …
efficacy and underlying safety problems have limited their clinical application. Herein …
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