Animal models of cigarette smoke-induced chronic obstructive pulmonary disease
JL Wright, A Churg - Expert review of respiratory medicine, 2010 - Taylor & Francis
Chronic exposure of laboratory animals to cigarette smoke reproduces many of the
anatomic/physiologic lesions (emphysema, small-airway remodeling and pulmonary …
anatomic/physiologic lesions (emphysema, small-airway remodeling and pulmonary …
Animal models of cigarette smoke-induced chronic obstructive lung disease
A Churg, JL Wright - Models of exacerbations in asthma and COPD, 2007 - karger.com
Recent years have seen an explosion of animal models of cigarette smoke-induced chronic
obstructive lung disease (COPD). Almost all of these have concentrated on the induction …
obstructive lung disease (COPD). Almost all of these have concentrated on the induction …
Testing drugs in animal models of cigarette smoke–induced chronic obstructive pulmonary disease
A Churg, JL Wright - Proceedings of the American Thoracic Society, 2009 - atsjournals.org
Animal models of cigarette smoke–induced chronic obstructive pulmonary disease (COPD)
provide potentially useful ways to test drug therapies, either by direct administration of the …
provide potentially useful ways to test drug therapies, either by direct administration of the …
Everything prevents emphysema: are animal models of cigarette smoke–induced chronic obstructive pulmonary disease any use?
There is a very large number of experimental approaches that prevent cigarette smoke–
induced emphysema in laboratory animals, but the few similar treatments that have been …
induced emphysema in laboratory animals, but the few similar treatments that have been …
Animal models of cigarette smoke-induced COPD
JL Wright, A Churg - Chest, 2002 - Elsevier
Objectives To review the animal models of COPD, and to compare these data to those found
in humans. Results Smoke-induced animal models can produce emphysema, although the …
in humans. Results Smoke-induced animal models can produce emphysema, although the …
Animal models and mechanisms of tobacco smoke-induced chronic obstructive pulmonary disease (COPD)
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide, and its global health burden is increasing. COPD is characterized by …
worldwide, and its global health burden is increasing. COPD is characterized by …
Animal models of chronic obstructive pulmonary disease
JL Wright, M Cosio, A Churg - american journal of …, 2008 - journals.physiology.org
The mechanisms involved in the genesis of chronic obstructive pulmonary disease (COPD)
are poorly defined. This area is complicated and difficult to model because COPD consists of …
are poorly defined. This area is complicated and difficult to model because COPD consists of …
Animal models of chronic obstructive pulmonary disease
Introduction: Chronic obstructive pulmonary disease (COPD) is a leading global cause of
mortality and chronic morbidity. Inhalation of cigarette smoke is the principal risk factor for …
mortality and chronic morbidity. Inhalation of cigarette smoke is the principal risk factor for …
Long-term nose-only cigarette smoke exposure induces emphysema and mild skeletal muscle dysfunction in mice
M Rinaldi, K Maes… - Disease models & …, 2012 - journals.biologists.com
Mouse models of chronic obstructive pulmonary disease (COPD) focus on airway
inflammation and lung histology, but their use has been hampered by the lack of pulmonary …
inflammation and lung histology, but their use has been hampered by the lack of pulmonary …
[HTML][HTML] A novel nonhuman primate model of cigarette smoke–induced airway disease
F Polverino, M Doyle-Eisele, J McDonald… - The American Journal of …, 2015 - Elsevier
Small animal models of chronic obstructive pulmonary disease (COPD) have several
limitations for identifying new therapeutic targets and biomarkers for human COPD. These …
limitations for identifying new therapeutic targets and biomarkers for human COPD. These …