Cause of mortality and sarcopenia in patients with idiopathic pulmonary fibrosis receiving antifibrotic therapy

Y Suzuki, Y Aono, M Kono, H Hasegawa… - …, 2021 - Wiley Online Library
Background and objective Recent research has highlighted the fundamental role of
sarcopenia, characterized by loss of skeletal muscle mass and strength, with a risk of poor …

Survival and course of lung function in the presence or absence of antifibrotic treatment in patients with idiopathic pulmonary fibrosis: long-term results of the …

J Behr, A Prasse, H Wirtz, D Koschel… - European …, 2020 - Eur Respiratory Soc
Objective There is a paucity of observational data on antifibrotic therapy for idiopathic
pulmonary fibrosis (IPF). We aimed to assess the course of disease of IPF patients with and …

Frequency and impact on clinical outcomes of sarcopenia in patients with idiopathic pulmonary fibrosis

K Fujita, H Ohkubo, A Nakano, Y Mori… - Chronic Respiratory …, 2022 - journals.sagepub.com
Objectives Sarcopenia is a syndrome characterized by reduced muscle mass and function. It
is well-recognized as a complication in chronic diseases such as chronic obstructive …

Sarcopenia in idiopathic pulmonary fibrosis: a prospective study exploring prevalence, associated factors and diagnostic approach

P Faverio, A Fumagalli, S Conti, F Madotto, F Bini… - Respiratory …, 2022 - Springer
Background Sarcopenia gained importance in the evaluation of patients with chronic
respiratory diseases, including idiopathic pulmonary fibrosis (IPF), since it may impact …

[HTML][HTML] Body mass index—percent forced vital capacity—respiratory hospitalization: new staging for idiopathic pulmonary fibrosis patients

T Kishaba, H Nagano, Y Nei… - Journal of Thoracic …, 2016 - ncbi.nlm.nih.gov
Background Idiopathic pulmonary fibrosis (IPF) is relentless progressive interstitial lung
disease. Evaluating predictor of mortality for IPF patients is crucial. The aim of this study was …

Change in forced vital capacity and associated subsequent outcomes in patients with newly diagnosed idiopathic pulmonary fibrosis

WM Reichmann, YF Yu, D Macaulay, EQ Wu… - BMC pulmonary …, 2015 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a rare and serious disease characterized
by progressive lung-function loss. Limited evidence has been published on the impact of …

Forced Vital Capacity (FVC) decline, mortality and healthcare resource utilization in idiopathic pulmonary fibrosis

MI Lassenius, I Toppila, N Pöntynen… - European clinical …, 2020 - Taylor & Francis
Aim of the study: Potential care implications of antifibrotic reimbursement restrictions were
studied by forced vital capacity (FVC) decline, mortality and specialty care related healthcare …

Idiopathic pulmonary fibrosis patients with severe physiologic impairment: characteristics and outcomes

J Pastre, S Barnett, I Ksovreli, J Taylor, AW Brown… - Respiratory …, 2021 - Springer
Research question There is no widely accepted grading system for IPF disease severity,
although physiologic impairment based on pulmonary function testing is frequently …

[HTML][HTML] Effect of antifibrotic therapy on survival in patients with idiopathic pulmonary fibrosis

JA de Andrade, ML Neely, AS Hellkamp, DA Culver… - Clinical Therapeutics, 2023 - Elsevier
Purpose Real-world studies have reported reduced mortality in patients with idiopathic
pulmonary fibrosis (IPF) treated with antifibrotic therapy; however, the initiation or …

[HTML][HTML] Effect of continued antifibrotic therapy after forced vital capacity decline in patients with idiopathic pulmonary fibrosis; a real world multicenter cohort study

CJ Adams, S Shapera, CJ Ryerson, D Assayag… - Respiratory …, 2022 - Elsevier
Rationale Longitudinal data on the impact of continued, switched or discontinued antifibrotic
therapy in patients with idiopathic pulmonary fibrosis (IPF) who have disease progression is …