Diet-induced metabolic endotoxemia is an important factor in the development of many
chronic diseases in animals and man. The gut epithelium is an efficient barrier that prevents …

Metabolic endotoxemia is a condition in which blood lipopolysaccharide (LPS) levels are
elevated, regardless of the presence of obvious infection. It has been suggested to lead to …

Gut flora appears to act as an important determinant in the pathogenesis of inflammatory
induced obesity/T2DM. Endotoxin may act as the systemic insult, impacted by a high-fat diet …

Endotoxemia, characterized by an excess of circulating bacterial wall lipopolysaccharide, is
associated with systemic inflammation and the metabolic syndrome. Placing 8 healthy …

Obesity is associated with metabolic derangements in multiple tissues, which contribute to
the progression of insulin resistance and the metabolic syndrome. The underlying stimulus …

The human intestinal tract comprises a rich and complex microbial ecosystem. This intestinal
microbota provides a large reservoir of potentially toxic molecules, including bacterial …

Obesity is associated with significantly increased cardiovascular (CV) risk and mortality.
Several molecular mechanisms underlying this association have been implied, among …

Translocation of microbiome‐derived lipopolysaccharide (LPS) to the bloodstream
(metabolic endotoxaemia) is associated with a significantly increased risk of cardiovascular …

Lipopolysaccharides (LPSs) can promote metabolic endotoxemia, which is considered
inflammatory and metabolically detrimental based on Toll-like receptor (TLR) 4 agonists …

Diabetes and obesity are two metabolic diseases characterized by insulin resistance and a
low-grade inflammation. Seeking an inflammatory factor causative of the onset of insulin …