The profile of expression of the scaffold protein SG2NA (s) differs between cancer types and its interactome in normal vis-a-vis breast tumor tissues suggests its wide …
Striatin and SG2NA are scaffold proteins that form signaling complexes called STRIPAK. It
has been associated with developmental abnormalities, cancer, and several other diseases …
has been associated with developmental abnormalities, cancer, and several other diseases …
SG2NA enhances cancer cell survival by stabilizing DJ-1 and thus activating Akt
GK Tanti, S Pandey, SK Goswami - Biochemical and Biophysical Research …, 2015 - Elsevier
SG2NA in association with striatin and zinedin forms a striatin family of WD-40 repeat
proteins. This family of proteins functions as scaffold in different signal transduction …
proteins. This family of proteins functions as scaffold in different signal transduction …
Biophysical characterization of SG2NA variants and their interaction with DJ-1 and calmodulin in vitro
SG2NA was first discovered as nuclear autoantigen in lung and bladder cancer patient. It
was named SG2NA as its expression increases during S to G2 phase of cell cycle …
was named SG2NA as its expression increases during S to G2 phase of cell cycle …
[HTML][HTML] Striatin family proteins: the neglected scaffolds
The Striatin family of proteins constitutes Striatin, SG2NA, and Zinedin. Members of this
family of proteins act as a signaling scaffold due to the presence of multiple protein-protein …
family of proteins act as a signaling scaffold due to the presence of multiple protein-protein …
[HTML][HTML] Striatins and STRIPAK complex partners in clinical outcomes of patients with breast cancer and responses to drug treatment
Objective Striatins (STRNs) family, which contains three multi-domain scaffolding proteins,
are cornerstones of the striatins interacting phosphatase and kinase (STRIPAK) complex …
are cornerstones of the striatins interacting phosphatase and kinase (STRIPAK) complex …
SNHG6 is upregulated in primary breast cancers and promotes cell cycle progression in breast cancer-derived cell lines
A Jafari-Oliayi, MH Asadi - Cellular Oncology, 2019 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are known as RNAs that do not
encode proteins and that are more than 200 nucleotides in size. Previously, it has been …
encode proteins and that are more than 200 nucleotides in size. Previously, it has been …
Bioinformatic analysis reveals GSG2 as a potential target for breast cancer therapy
Z Ye, Z Zhang, L Fang, D Tian, X Liu - Open Life Sciences, 2019 - degruyter.com
Objective To explore the potential role of GSG2 in breast cancer progression. Methods The
mRNA expression, DNA copy number and clinical data used in this study were obtained …
mRNA expression, DNA copy number and clinical data used in this study were obtained …
[HTML][HTML] 3'untranslated regions (3'UTR) of Gelsolin mRNA displays anticancer effects in non-small cell lung cancer (NSCLC) cells
X Liu, X Huang, J Ma, L Li, H Hu, J Feng… - American Journal of …, 2021 - ncbi.nlm.nih.gov
RNA-based therapeutics has attracted substantial interest from both academics and
pharmaceutical companies. In this study, we investigated the function and the underlying …
pharmaceutical companies. In this study, we investigated the function and the underlying …
Cellular impacts of striatins and the STRIPAK complex and their roles in the development and metastasis in clinical cancers
Simple Summary The STRIPAK (striatin-interacting phosphatase and kinase) complex and
its central components, striatins (STRNs), have attracted significant interest with regard to …
its central components, striatins (STRNs), have attracted significant interest with regard to …
lncRNA SNHG3 promotes breast cancer progression by acting as a miR‑326 sponge Retraction in/10.3892/or. 2022.8255
H Zhang, N Wei, W Zhang, L Shen… - Oncology …, 2020 - spandidos-publications.com
Accumulating evidence suggests that long noncoding RNA (lncRNA) small nucleolar RNA
host gene 3 (SHNG3) plays crucial roles in the initiation and progression of various types of …
host gene 3 (SHNG3) plays crucial roles in the initiation and progression of various types of …