Genetics and epigenetics of self‐injurious thoughts and behaviors: systematic review of the suicide literature and methodological considerations

S Mirza, AR Docherty, A Bakian, H Coon… - American Journal of …, 2022 - Wiley Online Library
Suicide is a multifaceted and poorly understood clinical outcome, and there is an urgent
need to advance research on its phenomenology and etiology. Epidemiological studies …

Genetic contributions to suicidal thoughts and behaviors

E DiBlasi, J Kang, AR Docherty - Psychological medicine, 2021 - cambridge.org
Suicidal ideation, suicide attempt (SA) and suicide are significantly heritable phenotypes.
However, the extent to which these phenotypes share genetic architecture is unclear. This …

Epigenetic studies in suicidal ideation and behavior

O Dada, J Qian, N Al-Chalabi, NJ Kolla, A Graff… - Psychiatric …, 2021 - journals.lww.com
Most psychiatric disorders are associated with an elevated risk of suicide. Suicidal behavior
is the product of the interaction of many risk factors, such as genetics and environmental …

Identification of novel, replicable genetic risk loci for suicidal thoughts and behaviors among US military veterans

NA Kimbrel, AE Ashley-Koch, XJ Qin… - JAMA …, 2023 - jamanetwork.com
Importance Suicide is a leading cause of death; however, the molecular genetic basis of
suicidal thoughts and behaviors (SITB) remains unknown. Objective To identify novel …

Neuropathology of suicide: recent findings and future directions

PE Lutz, N Mechawar, G Turecki - Molecular psychiatry, 2017 - nature.com
Suicide is a major public health concern and a leading cause of death in most societies.
Suicidal behaviour is complex and heterogeneous, likely resulting from several causes. It …

Overlapping genetic and environmental influences on nonsuicidal self-injury and suicidal ideation: different outcomes, same etiology?

DF Maciejewski, HE Creemers, MT Lynskey… - JAMA …, 2014 - jamanetwork.com
Importance Nonsuicidal self-injury (NSSI) and suicidal self-injury are very harmful behaviors
and are associated with several psychiatric disorders. In the recently developed fifth edition …

[HTML][HTML] Brain and blood transcriptome profiles delineate common genetic pathways across suicidal ideation and suicide

S Sun, Q Liu, Z Wang, Y Huang, ME Sublette… - Molecular …, 2024 - nature.com
Human genetic studies indicate that suicidal ideation and behavior are both heritable. Most
studies have examined associations between aberrant gene expression and suicide …

Epigenetic studies of suicidal behavior

A Bani-Fatemi, AS Howe, V De Luca - Neurocase, 2015 - Taylor & Francis
Recent studies have shown an association between gene alterations by epigenetic
mechanisms and suicidal behavior. These epigenetic mechanisms are mitotically, and in …

[HTML][HTML] Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program

AE Ashley-Koch, NA Kimbrel, XJ Qin, JH Lindquist… - PLoS …, 2023 - journals.plos.org
Suicidal ideation (SI) often precedes and predicts suicide attempt and death, is the most
common suicidal phenotype and is over-represented in veterans. The genetic architecture of …

[HTML][HTML] Toward fine-grained phenotyping of suicidal behavior: the role of suicidal subtypes

JA Bernanke, BH Stanley, MA Oquendo - Molecular psychiatry, 2017 - nature.com
Despite advances in the assessment and management of suicidal behavior (SB), suicide
remains a leading cause of morbidity and mortality in the United States, and suicide rates …