Genetics and epigenetics of self‐injurious thoughts and behaviors: systematic review of the suicide literature and methodological considerations
Suicide is a multifaceted and poorly understood clinical outcome, and there is an urgent
need to advance research on its phenomenology and etiology. Epidemiological studies …
need to advance research on its phenomenology and etiology. Epidemiological studies …
Genetic contributions to suicidal thoughts and behaviors
Suicidal ideation, suicide attempt (SA) and suicide are significantly heritable phenotypes.
However, the extent to which these phenotypes share genetic architecture is unclear. This …
However, the extent to which these phenotypes share genetic architecture is unclear. This …
Epigenetic studies in suicidal ideation and behavior
Most psychiatric disorders are associated with an elevated risk of suicide. Suicidal behavior
is the product of the interaction of many risk factors, such as genetics and environmental …
is the product of the interaction of many risk factors, such as genetics and environmental …
Identification of novel, replicable genetic risk loci for suicidal thoughts and behaviors among US military veterans
NA Kimbrel, AE Ashley-Koch, XJ Qin… - JAMA …, 2023 - jamanetwork.com
Importance Suicide is a leading cause of death; however, the molecular genetic basis of
suicidal thoughts and behaviors (SITB) remains unknown. Objective To identify novel …
suicidal thoughts and behaviors (SITB) remains unknown. Objective To identify novel …
Neuropathology of suicide: recent findings and future directions
Suicide is a major public health concern and a leading cause of death in most societies.
Suicidal behaviour is complex and heterogeneous, likely resulting from several causes. It …
Suicidal behaviour is complex and heterogeneous, likely resulting from several causes. It …
Overlapping genetic and environmental influences on nonsuicidal self-injury and suicidal ideation: different outcomes, same etiology?
DF Maciejewski, HE Creemers, MT Lynskey… - JAMA …, 2014 - jamanetwork.com
Importance Nonsuicidal self-injury (NSSI) and suicidal self-injury are very harmful behaviors
and are associated with several psychiatric disorders. In the recently developed fifth edition …
and are associated with several psychiatric disorders. In the recently developed fifth edition …
[HTML][HTML] Brain and blood transcriptome profiles delineate common genetic pathways across suicidal ideation and suicide
Human genetic studies indicate that suicidal ideation and behavior are both heritable. Most
studies have examined associations between aberrant gene expression and suicide …
studies have examined associations between aberrant gene expression and suicide …
Epigenetic studies of suicidal behavior
A Bani-Fatemi, AS Howe, V De Luca - Neurocase, 2015 - Taylor & Francis
Recent studies have shown an association between gene alterations by epigenetic
mechanisms and suicidal behavior. These epigenetic mechanisms are mitotically, and in …
mechanisms and suicidal behavior. These epigenetic mechanisms are mitotically, and in …
[HTML][HTML] Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program
AE Ashley-Koch, NA Kimbrel, XJ Qin, JH Lindquist… - PLoS …, 2023 - journals.plos.org
Suicidal ideation (SI) often precedes and predicts suicide attempt and death, is the most
common suicidal phenotype and is over-represented in veterans. The genetic architecture of …
common suicidal phenotype and is over-represented in veterans. The genetic architecture of …
[HTML][HTML] Toward fine-grained phenotyping of suicidal behavior: the role of suicidal subtypes
JA Bernanke, BH Stanley, MA Oquendo - Molecular psychiatry, 2017 - nature.com
Despite advances in the assessment and management of suicidal behavior (SB), suicide
remains a leading cause of morbidity and mortality in the United States, and suicide rates …
remains a leading cause of morbidity and mortality in the United States, and suicide rates …