Objectives Dental calculus is among the richest known sources of ancient DNA in the
archaeological record. Although most DNA within calculus is microbial, it has been shown to …

Objectives Archaeological dental calculus is a rich source of host‐associated biomolecules.
Importantly, however, dental calculus is more accurately described as a calcified microbial …

Dental calculus (calcified dental plaque) is prevalent in archaeological skeletal collections
and is a rich source of oral microbiome and host-derived ancient biomolecules. Recently, it …

Dental calculus from archaeological samples is a rich source of ancient biomolecules, such
as DNA, proteins, and microremains, mainly related to food. Focusing on different contents …

Ancient DNA sampling methods—although optimized for efficient DNA extraction—are
destructive, relying on drilling or cutting and powdering (parts of) bones and teeth. As the …

Archaeological materials are a finite resource, and efforts should be made to minimize
destructive analyses. This can be achieved by using protocols combining extraction of …

Poor DNA preservation is the most limiting factor in ancient genomic research. In the
majority of ancient bones and teeth, endogenous DNA molecules represent a minor fraction …

Dental calculus (calcified tartar or plaque) is today widespread on modern human teeth
around the world. A combination of soft starchy foods, changing acidity of the oral …

Dental calculus and other preserved microbiome substrates are an attractive target for
dietary reconstruction in past populations through a variety of physical, chemical, and …

Although great progress has been made in improving methods for generating DNA
sequences from ancient biological samples, many, if not most, samples are still not …