Dysregulation of dopamine transporters (DAT) within the dopaminergic system is an
important biomarker of cocaine exposure. Depending on cocaine amount in‐taken, one …

Cocaine blocks dopamine uptake via dopamine transporter (DAT) on plasma membrane of
neuron cells and, as a result, produces the high and induces DAT trafficking to plasma …

The profound alterations produced by cocaine on dopamine (DA) neurotransmission raise
the possibility that dopamine transporter (DAT)-expressing neurons may modify DA transport …

As well known, cocaine induces stimulant effects and dopamine transporter (DAT) trafficking
to the plasma membrane of dopaminergic neurons. In the present study, we examined …

Several studies have shown that repeated cocaine administration, followed by withdrawal,
alters dopamine transporter (DAT) levels in the rat. These changes must arise from changes …

In HEK 293 cells expressing the human dopamine transporter (DAT), a 10-min incubation
with 10 μM cocaine followed by extensive washing resulted in a 30% increase in [3H] …

Several classes of drugs bind to the dopamine transporter (DAT) with high affinity, but some
are weaker positive reinforcers than cocaine, suggesting that affinity for and occupancy of …

Cocaine binds with the dopamine transporter (DAT), an effect that has been extensively
implicated in its reinforcing effects. However, persisting adaptations in DAT regulation after …

In order to determine whether repeated cocaine administration produced persistent changes
in dopamine (DA) receptor binding and release consistent with behavioral sensitization, rats …

Rationale Behavioural sensitization is a long lasting phenomenon that has been proposed
to be involved in drug addiction. Although the expression of cocaine-induced sensitization …