Vaccinia virus (VACV) has been used extensively as the vaccine against smallpox and as a
viral vector for the development of recombinant vaccines and cancer therapies. Replication …

Replication-competent viruses, such as Vaccinia virus (VACV), are powerful tools for the
development of oncolytic viral therapies and elicit superior immune responses when used …

Vaccinia virus (VACV) was successfully used as a vaccine in the smallpox eradication
campaign. Since then, it has been widely used in the development of vaccine and …

In 1796, Edward Jenner introduced the concept of vaccination with cowpox virus, an
Orthopoxvirus within the family Poxviridae that elicits cross protective immunity against …

The past few years have seen a rash of emerging viral diseases, including the Ebola crisis in
West Africa, the pandemic spread of chikungunya, and the recent explosion of Zika in South …

Various vaccinia virus (VACV) strains were applied during the smallpox vaccination
campaign to eradicate the variola virus worldwide. After the eradication of smallpox, VACV …

Vaccinia virus (VACV) has been used more extensively for human immunization than any
other vaccine. For almost two centuries, VACV was employed to provide cross-protection …

Viruses are used as expression vectors for protein synthesis, immunology research,
vaccines, and therapeutics. Advantages of poxvirus vectors include the accommodation of …

Vaccinia virus (VACV) has been used as the vaccine to protect against smallpox, and
recombinant VACVs have been used to develop vaccine candidates against numerous …

Vaccinia virus, effectively used for immunization against smallpox, now serves as a
recombinant vector for the development of vaccines against other infectious agents and …