Digging into the low molecular weight peptidome with the OligoNet web server

Y Liu, S Forcisi, M Lucio, M Harir, F Bahut… - Scientific Reports, 2017 - nature.com
Bioactive peptides play critical roles in regulating many biological processes. Recently,
natural short peptides biomarkers are drawing significant attention and are considered as …

ProtPipe: A Multifunctional Data Analysis Pipeline for Proteomics and Peptidomics

ZL Li, C Weller, S Shah, N Johnson, Y Hao, J Roberts… - bioRxiv, 2023 - biorxiv.org
Mass spectrometry (MS) is a technique widely employed for the identification and
characterization of proteins, personalized medicine, systems biology and biomedical …

Combining mass spectrometry and machine learning to discover bioactive peptides

CT Madsen, JC Refsgaard, FG Teufel… - Nature …, 2022 - nature.com
Peptides play important roles in regulating biological processes and form the basis of a
multiplicity of therapeutic drugs. To date, only about 300 peptides in human have confirmed …

Peptipedia: a user-friendly web application and a comprehensive database for peptide research supported by machine learning approach

C Quiroz, YB Saavedra, B Armijo-Galdames… - Database, 2021 - academic.oup.com
Peptides have attracted attention during the last decades due to their extraordinary
therapeutic properties. Different computational tools have been developed to take …

protti: an R package for comprehensive data analysis of peptide-and protein-centric bottom-up proteomics data

JP Quast, D Schuster, P Picotti - Bioinformatics Advances, 2022 - academic.oup.com
We present a flexible, user-friendly R package called protti for comprehensive quality
control, analysis and interpretation of quantitative bottom-up proteomics data. protti supports …

Expanding the dipeptidyl peptidase 4-regulated peptidome via an optimized peptidomics platform

AD Tinoco, DM Tagore… - Journal of the American …, 2010 - ACS Publications
In recent years, the biological sciences have seen a surge in the development of methods,
including high-throughput global methods, for the quantitative measurement of biomolecule …

PDAUG: a Galaxy based toolset for peptide library analysis, visualization, and machine learning modeling

J Joshi, D Blankenberg - BMC bioinformatics, 2022 - Springer
Background Computational methods based on initial screening and prediction of peptides
for desired functions have proven to be effective alternatives to lengthy and expensive …

pepFunk: a tool for peptide-centric functional analysis of metaproteomic human gut microbiome studies

CMA Simopoulos, Z Ning, X Zhang, L Li… - …, 2020 - academic.oup.com
Motivation Enzymatic digestion of proteins before mass spectrometry analysis is a key
process in metaproteomic workflows. Canonical metaproteomic data processing pipelines …

The Immunopeptidomics Ontology (ImPO)

D Faria, P Eugénio, M Contreiras Silva, L Balbi… - Database, 2024 - academic.oup.com
The adaptive immune response plays a vital role in eliminating infected and aberrant cells
from the body. This process hinges on the presentation of short peptides by major …

Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics

M Wilhelm, DP Zolg, M Graber, S Gessulat… - Nature …, 2021 - nature.com
Characterizing the human leukocyte antigen (HLA) bound ligandome by mass spectrometry
(MS) holds great promise for developing vaccines and drugs for immune-oncology. Still, the …