Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions
Z Megyesfalvi, CM Gay, H Popper… - CA: a cancer journal …, 2023 - Wiley Online Library
Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity.
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
[HTML][HTML] Small cell lung cancer: can recent advances in biology and molecular biology be translated into improved outcomes?
Small cell lung cancer (SCLC) is one of the four major histological types of lung cancer. The
incidence of SCLC in developed countries has declined in recent years, presumably …
incidence of SCLC in developed countries has declined in recent years, presumably …
Small cell lung cancer: where do we go from here?
Small cell lung cancer (SCLC) is an aggressive disease that accounts for approximately
14% of all lung cancers. In the United States, approximately 31,000 patients are diagnosed …
14% of all lung cancers. In the United States, approximately 31,000 patients are diagnosed …
Advances in small cell lung cancer
GP Kalemkerian, BJ Schneider - Hematology/Oncology …, 2017 - hemonc.theclinics.com
Small cell lung cancer (SCLC) is an aggressive neuroendocrine tumor with clinical and
pathologic characteristics distinct from those of non-SCLC. The primary cause of SCLC is …
pathologic characteristics distinct from those of non-SCLC. The primary cause of SCLC is …
[HTML][HTML] Small cell lung cancer (SCLC): no treatment advances in recent years
F Koinis, A Kotsakis, V Georgoulias - Translational lung cancer …, 2016 - ncbi.nlm.nih.gov
Small cell lung cancer (SCLC) is an aggressive malignancy with a distinct natural history
and dismal prognosis. Given its predisposition for early dissemination, patients are …
and dismal prognosis. Given its predisposition for early dissemination, patients are …
[HTML][HTML] Targeted therapies and biomarkers in small cell lung cancer
Small cell lung cancer (SCLC) is an aggressive malignancy characterized by rapid growth,
early metastasis, and acquired therapeutic resistance. A majority of patients with SCLC have …
early metastasis, and acquired therapeutic resistance. A majority of patients with SCLC have …
[HTML][HTML] Small cell lung cancer: novel treatments beyond immunotherapy
JJ Meijer, A Leonetti, G Airò, M Tiseo, C Rolfo… - Seminars in cancer …, 2022 - Elsevier
Small cell lung cancer (SCLC) arises in peribronchial locations and infiltrates the bronchial
submucosa, including about 15% of lung cancer cases. Despite decades of research, the …
submucosa, including about 15% of lung cancer cases. Despite decades of research, the …
Small cell lung cancer
EB Bernhardt, SI Jalal - Lung cancer: Treatment and research, 2016 - Springer
Small cell lung cancer (SCLC) is an aggressive cancer of neuroendocrine origin, which is
strongly associated with cigarette smoking. Patients typically present with a short duration of …
strongly associated with cigarette smoking. Patients typically present with a short duration of …
Small-cell lung cancer: what we know, what we need to know and the path forward
Small-cell lung cancer (SCLC) is a deadly tumour accounting for approximately 15% of lung
cancers and is pathologically, molecularly, biologically and clinically very different from other …
cancers and is pathologically, molecularly, biologically and clinically very different from other …
[HTML][HTML] Update on the biology, management, and treatment of small cell lung cancer (SCLC)
A Saltos, M Shafique, A Chiappori - Frontiers in oncology, 2020 - frontiersin.org
Small-cell lung cancer (SCLC) accounts for 13–15% of all new lung cancer cases in the US.
The tumor has a tendency to disseminate early resulting in 80–85% of patients being …
The tumor has a tendency to disseminate early resulting in 80–85% of patients being …