Background Platelet transfusions are used to prevent and treat bleeding in people who are
thrombocytopenic. Despite improvements in donor screening and laboratory testing, a small …

Background Platelet transfusions are used to prevent and treat bleeding in patients who are
thrombocytopenic. Despite improvements in donor screening and laboratory testing, a small …

Pathogen inactivation of platelet concentrates reduces the risk for blood-borne infections.
However, its effect on platelet function and hemostatic efficacy of transfusion is unclear. We …

BACKGROUND: A recent independently funded randomized controlled trial (RCT; Br J
Haematol 2010; 150: 209‐17) questioned prevailing opinion concerning the hemostatic …

Background The eligibility criteria of a previously reported meta‐analysis (Transfusion 2011;
51: 1058–1071) of randomized controlled trials (RCTs) of pathogen reduction of platelets in …

Platelet transfusions are commonly administered for the prevention or treatment of bleeding
in patients with acquired thrombocytopenia across a range of clinical contexts. Recent data …

Background People with thrombocytopenia often require a surgical procedure. A low platelet
count is a relative contraindication to surgery due to the risk of bleeding. Platelet …

BACKGROUND Two noninferiority, randomized, controlled trials were conducted in parallel
comparing the safety and efficacy of platelets treated with Intercept or Mirasol pathogen …

Background Platelet transfusions are used in modern clinical practice to prevent and treat
bleeding in people who are thrombocytopenic due to bone marrow failure. Although …

Background People with thrombocytopenia due to bone marrow failure are vulnerable to
bleeding. Platelet transfusions have limited efficacy in this setting and alternative agents that …