[HTML][HTML] Multi-omics reveal disturbance of glucose homeostasis in pregnant rats exposed to short-chain perfluorobutanesulfonic acid

G Yu, T Luo, Y Liu, X Huo, C Mo, B Huang, Y Li… - Ecotoxicology and …, 2024 - Elsevier
Perfluorobutanesulfonic acid (PFBS), a short-chain alternative to perfluorooctanesulfonic
acid (PFOS), is widely used in various products and is increasingly present in environmental …

[HTML][HTML] Metabolic perturbations in pregnant rats exposed to low-dose perfluorooctanesulfonic acid: an integrated multi-omics analysis

G Yu, J Wang, Y Liu, T Luo, X Meng, R Zhang… - Environment …, 2023 - Elsevier
Emerging epidemiological evidence has linked per-and polyfluoroalkyl substances (PFAS)
exposure could be linked to the disturbance of gestational glucolipid metabolism, but the …

Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat …

X Meng, G Yu, T Luo, R Zhang, J Zhang, Y Liu - Chemosphere, 2023 - Elsevier
Emerging epidemiological evidence indicates potential associations between gestational
perfluorobutane sulfonate (PFBS) exposure and adverse metabolic outcomes in offspring …

[HTML][HTML] Exposure to legacy and novel perfluoroalkyl substance disturbs the metabolic homeostasis in pregnant women and fetuses: A metabolome-wide association …

Y Li, X Lu, N Yu, A Li, T Zhuang, L Du, S Tang… - Environment …, 2021 - Elsevier
Abstract Background Perfluoroalkyl substances (PFASs) exist extensively and several of
these have been verified to be toxic. Prenatal exposure to PFASs has attracted much …

[HTML][HTML] Structure-based investigation on the association between perfluoroalkyl acids exposure and both gestational diabetes mellitus and glucose homeostasis in …

X Liu, L Zhang, L Chen, J Li, Y Wang, J Wang… - Environment …, 2019 - Elsevier
Background Biomonitoring studies have shown the presence of structurally diverse
perfluoroalkyl acids (PFAAs) in humans but only a few studies are available regarding the …

Exposure to per-and polyfluoroalkyl substances as a risk factor for gestational diabetes mellitus through interference with glucose homeostasis

C Xu, L Zhang, Q Zhou, J Ding, S Yin, X Shang… - Science of The Total …, 2022 - Elsevier
Per-and polyfluoroalkyl substances (PFASs) are hypothesized to trigger gestational diabetes
mellitus (GDM) through modulation of glucose metabolism. However, studies investigating …

Perinatal exposure to perfluorooctane sulfonate affects glucose metabolism in adult offspring

HT Wan, YG Zhao, PY Leung, CKC Wong - PloS one, 2014 - journals.plos.org
Perfluoroalkyl acids (PFAAs) are globally present in the environment and are widely
distributed in human populations and wildlife. The chemicals are ubiquitous in human body …

Insights from metabolomics and transcriptomics studies on Perfluorohexanesulfonic acid (PFHxS) exposed zebrafish embryos

ZS Ulhaq, DAT Boncan, TF Chan, WKF Tse - Science of the Total …, 2023 - Elsevier
Perfluorohexanesulfonic acid (PFHxS) is a short-chain perfluoroalkyl substance widely used
to replace the banned perfluorooctanesulfonic acid (PFOS) in various industrial and …

Evaluating the effect of gestational exposure to perfluorohexane sulfonate on placental development in mice combining alternative splicing and gene expression …

Y Zhang, J Lv, YJ Fan, L Tao, J Xu… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Perfluorohexane sulfonate (PFHxS) is a frequently detected per-and
polyfluoroalkyl substance in most populations, including in individuals who are pregnant, a …

Exposure to per-and polyfluoroalkyl substances in early pregnancy, risk of gestational diabetes mellitus, potential pathways, and influencing factors in pregnant …

L Zang, X Liu, X Xie, X Zhou, Y Pan, J Dai - Environmental Pollution, 2023 - Elsevier
Although previous studies have reported an association between maternal serum
perfluoroalkyl substance (PFAS) exposure and gestational diabetes mellitus (GDM) risk …