Extracellular vesicles in the pathogenesis and treatment of acute lung injury

Q Hu, S Zhang, Y Yang, JQ Yao, WF Tang… - Military Medical …, 2022 - Springer
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common life-
threatening lung diseases associated with acute and severe inflammation. Both have high …

Extracellular vesicles: a new frontier for research in acute respiratory distress syndrome

RY Mahida, S Matsumoto… - American journal of …, 2020 - atsjournals.org
Recent research on extracellular vesicles (EVs) has provided new insights into
pathogenesis and potential therapeutic options for acute respiratory distress syndrome …

Functional evidence of pulmonary extracellular vesicles in infectious and noninfectious lung inflammation

H Lee, D Zhang, DL Laskin, Y Jin - The Journal of Immunology, 2018 - journals.aai.org
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a highly complex
process that can be triggered by both noninfectious (sterile) and infectious stimuli …

[HTML][HTML] Emerging role of extracellular vesicles in lung injury and inflammation

Z Lanyu, H Feilong - biomedicine & pharmacotherapy, 2019 - Elsevier
Lung injury and inflammation are common characterizes in many pulmonary diseases.
Alveolar epithelial cells, macrophages, pulmonary microvascular endothelial cells, and …

Mesenchymal stem cell-derived extracellular vesicles for the treatment of acute respiratory distress syndrome

A Abraham, A Krasnodembskaya - Stem Cells Translational …, 2020 - academic.oup.com
Acute respiratory distress syndrome (ARDS) is a serious and potentially fatal acute
inflammatory lung condition which currently has no specific treatments targeting its …

Extracellular vesicle: an emerging mediator of intercellular crosstalk in lung inflammation and injury

H Lee, E Abston, D Zhang, A Rai, Y Jin - Frontiers in immunology, 2018 - frontiersin.org
Inflammatory lung responses are one of the characterized features in the pathogenesis of
many lung diseases, including acute respiratory distress syndrome (ARDS) and chronic …

Role of extracellular vesicles in cell death and inflammation

R Sanwlani, L Gangoda - Cells, 2021 - mdpi.com
Extracellular vesicles (EVs) have been identified as novel mediators of intercellular
communication. They work via delivering the sequestered cargo to cells in the close vicinity …

Extracellular vesicles derived from mesenchymal stromal cells: a therapeutic option in respiratory diseases?

SC Abreu, DJ Weiss, PRM Rocco - Stem cell research & therapy, 2016 - Springer
Extracellular vesicles (EVs) are plasma membrane-bound fragments released from several
cell types, including mesenchymal stromal cells (MSCs), constitutively or under stimulation …

Pulmonary extracellular vesicles as mediators of local and systemic inflammation

CJE Wahlund, A Eklund, J Grunewald… - Frontiers in cell and …, 2017 - frontiersin.org
Cells of the airways are constantly exposed to environmental hazards including cigarette
smoke, irritants, pathogens, and mechanical insults. Maintaining barrier integrity is vital, and …

[HTML][HTML] Caspase-1-mediated extracellular vesicles derived from pyroptotic alveolar macrophages promote inflammation in acute lung injury

X Qin, Y Zhou, C Jia, Z Chao, H Qin… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
The occurrence and development of acute lung injury (ALI) involve a variety of pathological
factors and complex mechanisms. How pulmonary cells communicate with each other and …