Iron is a crucial element for mammalian cells, considering its intervention in several
physiologic processes. Its homeostasis is finely regulated, and its alteration could be …

Since iron can contribute to detrimental radical generating processes through the Fenton
and Haber‐Weiss reactions, it seems to be a reasonable approach to modulate iron‐related …

Biological iron is necessary for vital functions and also potentially toxic to the organisms.
This dual effect raised the interest of many investigators to study the mechanisms controlling …

Inflammation, being a hallmark of many chronic diseases, including cancer, inflammatory
bowel disease, rheumatoid arthritis, and chronic kidney disease, negatively affects iron …

Both, mammalian cells and microbes have an essential need for iron, which is required for
many metabolic processes and for microbial pathogenicity. In addition, cross-regulatory …

Iron is a redox active metal involved in the oxidation-reduction reactions and regulation of
cell growth and differentiation. Iron is an integral part of many proteins and enzymes that …

Iron-chelation therapy has its origins in the treatment of iron-overload syndromes. For many
years, the standard for this purpose has been deferoxamine. Recently, considerable …

Atherosclerosis being a leading death cause in many countries is a chronic inflammatory
process in which inflammation, immune activation, and oxidative stress are interactively …

Over 2 billion people in both developing as well as developed countries–over 30% of the
world's population–are anaemic. With the classical preconception that oral iron …

Iron is an essential mineral that serves as a prosthetic group for a variety of proteins involved
in vital cellular processes. The iron economy within humans is highly conserved in that there …