Severe osteogenesis imperfecta (OI) is a hereditary disorder characterized by increased
bone fragility and progressive bone deformity. Cyclical pamidronate infusions improve …

Context: Cyclical iv pamidronate is a widely used symptomatic therapy of osteogenesis
imperfecta (OI). What happens after treatment discontinuation is unknown. Objective: The …

Clinical and histomorphometric outcome was compared between children with OI who had
received pamidronate since infancy and age‐matched patients who had never received …

Objectives. Treatment with pamidronate improves the clinical course in children with
osteogenesis imperfecta (OI), but theoretically might affect longitudinal growth. In this study …

Context: Intravenous pamidronate treatment is beneficial to children and adolescents with
osteogenesis imperfecta (OI), but the effects of prolonged therapy are not well characterized …

Background Severe osteogenesis imperfecta is a disorder characterized by osteopenia,
frequent fractures, progressive deformity, loss of mobility, and chronic bone pain. There is no …

Severe forms of osteogenesis imperfecta (OI) are characterised by osteoporosis with
multiple fractures, deformity, progressive loss of mobility and chronic bone pain …

Cyclical intravenous pamidronate is a widely used symptomatic therapy in moderate to
severe osteogenesis imperfecta (OI). The effects of treatment discontinuation on long bone …

Cyclical iv therapy with pamidronate improves the clinical course in children and
adolescents with osteogenesis imperfecta (OI). In this study we evaluated the effect of this …

INTRODUCTION: Bone mineral density (BMD) and fracture rates in children with
osteogenesis imperfecta (OI) have been shown to improve with bisphosphonate therapy …