Ultrasensitive biosensor for microRNA-155 using synergistically catalytic nanoprobe coupled with improved cascade strand displacement reaction

Z Liang, D Ou, D Sun, Y Tong, H Luo, Z Chen - Biosensors and …, 2019 - Elsevier
MicroRNAs, essential for gene expression and physiological regulation, are considered to
be reliable biomarkers for the early diagnosis and treatment of cancers. Herein, a sensitive …

DNA-functionalized metal-organic framework ratiometric nanoprobe for MicroRNA detection and imaging in live cells

Q Han, D Zhang, R Zhang, J Tang, K Xu, M Shao… - Sensors and Actuators B …, 2022 - Elsevier
MicroRNAs are short noncoding regulatory RNAs that are increasingly used as disease
biomarkers. Rapid, sensitive, and quantitative microRNAs detection methods with high …

A generic and non-enzymatic electrochemical biosensor integrated molecular beacon-like catalyzed hairpin assembly circuit with MOF@ Au@ G-triplex/hemin …

Y Li, C Zhang, Y He, J Gao, W Li, L Cheng… - Biosensors and …, 2022 - Elsevier
MicroRNAs (miRNAs) have been extensively studied as circulating biomarkers for early
diagnosis and prognosis of many human diseases. However, it has been found challenging …

Dual-model photoelectrochemical biosensor via DNAzyme walker integrated nanoprobe for ultrasensitive ratiometric detection of microRNA-155

L Tian, J Zhang, Y Zhang, H Fan, C Liu, Y Wang… - Sensors and Actuators B …, 2023 - Elsevier
Ultrasensitive detection for low concentration and abnormal expression of microRNA-155
(miR-155) in serum (fM level) at the early stage of cancer still exist great challenges …

An electrochemical biosensor for sensitive detection of microRNA-155: combining target recycling with cascade catalysis for signal amplification

X Wu, Y Chai, P Zhang, R Yuan - ACS applied materials & …, 2015 - ACS Publications
In this work, a new electrochemical biosensor based on catalyzed hairpin assembly target
recycling and cascade electrocatalysis (cytochrome c (Cyt c) and alcohol oxidase (AOx)) for …

Construction of a novel biosensor based on the self-assembly of dual-enzyme cascade amplification-induced copper nanoparticles for ultrasensitive detection of …

J Cui, H Han, J Piao, H Shi, D Zhou… - … applied materials & …, 2020 - ACS Publications
MicroRNAs (miRNAs) have received extensive attention because of their potential as
biomarkers for cancer diagnosis and monitoring, and their effective detection is very …

An ultrasensitive electrochemical biosensor integrated by nicking endonuclease-assisted primer exchange reaction cascade amplification and DNA nanosphere …

S Yu, S Chen, Y Dang, Y Zhou, JJ Zhu - Analytical Chemistry, 2022 - ACS Publications
Specific and sensitive microRNAs (miRNAs) detection is essential to early cancer diagnosis.
The development of these technologies including functional nuclease-mediated target …

Label-free fluorescent detection of microRNA-155 based on synthesis of hairpin DNA-templated copper nanoclusters by etching (top-down approach)

YS Borghei, M Hosseini, MR Ganjali… - Sensors and Actuators B …, 2017 - Elsevier
In this study, we have reported a new approach for sequence specific microRNA-155
(miRNA-155) detection by water soluble luminescent copper nanoclusters. The method is …

Sensitive electrochemical biosensor for MicroRNAs based on duplex-specific nuclease-assisted target recycling followed with gold nanoparticles and enzymatic …

H Zhang, M Fan, J Jiang, Q Shen, C Cai, J Shen - Analytica chimica acta, 2019 - Elsevier
The detection of sequence-specific microRNAs (miRNAs) is an important factor to the
diseases diagnosis. Herein, a triple signal amplification electrochemical biosensor for highly …

Dual-mode corroborative detection of miRNA-21 based on catalytic hairpin assembly reaction and oxygen reduction reaction combined strategy for the signal …

X Ma, Y Ma, O Ejeromedoghene… - Sensors and Actuators B …, 2022 - Elsevier
Here, we first combined the catalytic hairpin assembly (CHA) reaction and oxygen reduction
reaction (ORR) to amplify the electrochemical signal for the determination of miRNA-21. In …